Possible therapy in hereditary angioneurotic edema (HAE)

Mögliche neue Therapie beim hereditären angioneurotischen Ödem

Summary

The symptomatic therapy of hereditary angioneurotic edema with tranexamic acid and suramin in two patients is reported. The first patient responded well to tranexamic acid (Cyclocapron®) but not to suramin. In the second patient, attacks of edema could apparently be better prevented with suramin.

Zusammenfassung

Es wird über die symptomatische Therapie des hereditären angioneurotischen Ödems mit Tranexamsäure und Suramin bei zwei Patienten berichtet. Während der erste Patient gut auf eine Therapie mit Tranexamsäure (Cyclocapron®), nicht jedoch auf Suramin ansprach, ließen sich beim zweiten Patienten die Ödemanfälle mit Suramin unterbinden.

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This work was supported in part by Schweiz. Nationalfonds zur Förderung der wissenschaftlichen Forschung, Credit No 3.479.70.

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Brackertz, D., Kueppers, F. Possible therapy in hereditary angioneurotic edema (HAE). Klin Wochenschr 51, 620–622 (1973). https://doi.org/10.1007/BF01468576

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Key words

  • Hereditary angioneurotic edema
  • tranexamic acid
  • suramin
  • C\(\bar 1\)-inhibitor

Schlüsselwörter

  • Hereditäres angioneurotisches Ödem
  • Tranexamsäure
  • Suramin
  • C\(\bar 1\)-Inhibitor