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Endogene Fibrinolyseinhibitoren bei Lebercirrhosen

Endogenous inhibitors of fibrinolytic activity in liver cirrhosis

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Summary

In advanced cirrhosis of the liver a significant increase of the two antiplasmins a1-antitrypsin and a2-macroglobulin could be found. The urokinase inhibitor was similarly increased. However, the fibrinolytic activity in an inhibitor-free test system was elevated. The significance of these results in connection with endogenous fibrinolytic activity is discussed.

Zusammenfassung

Bei fortgeschrittenen Lebercirrhosen zeigte sich eine signifikante Vermehrung der Antiplasmine a1-Antitrypsin und a2-Makroglobulin. Gleichfalls erhöht war der Urokinase-Inhibitor. Im inhibitorfreien Testsystem dagegen war eine erhöhte Fibrinolyseaktivität nachweisbar.

Die Bedeutung dieser Untersuchungsergebnisse für die endogene Fibrinolyseaktivität wird diskutiert.

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Authors and Affiliations

  1. Medizinische Klinik der Universität Innsbruck, Austria

    R. Aschauer, F. Holzknecht & S. Platzer

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  1. R. Aschauer
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  2. F. Holzknecht
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  3. S. Platzer
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Aschauer, R., Holzknecht, F. & Platzer, S. Endogene Fibrinolyseinhibitoren bei Lebercirrhosen. Klin Wochenschr 51, 1170–1172 (1973). https://doi.org/10.1007/BF01468567

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  • DOI: https://doi.org/10.1007/BF01468567

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