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Plasmazellkolonien aus leukämischem Knochenmark in vitro

Cytologische and cytochemische Differenzierung

Plasma cell colonies from leukaemic bone marrow in vitro.

Differentiation by cytological and cytochemical methods

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Summary

Colonies which proliferated in agar culture from mononuclear blood and bone marrow cells of 42 normal persons and 7 patients with leukaemia have been investigated by means of cytological and cytochemical methods. In contrast to the cellular composition of normal colonies 3 patients with acute myeloid leukaemia and 1 patient with leukaemic reticulosis showed mixed colonies consisting of blasts and plasma cells.

Zusammenfassung

Koloniezellen, die bei der Aussaat von mononukleären Blut- und Knochenmarkszellen von 42 Normalpersonen und 7 Leukämiepatienten in Agargel entstanden, wurden cytologisch und cytochemisch untersucht. Abweichend von der cytologischen Zusammensetzung normaler Kolonien konnten bei 3 Patienten mit akuter myeloischer Leukämie und bei einem Patienten mit Retikulose gemischte Kolonien von Blasten und Plasmazellen nachgewiesen werden.

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Beckmann, H., Soltau, H., Garbrecht, M. et al. Plasmazellkolonien aus leukämischem Knochenmark in vitro. Klin Wochenschr 52, 603–605 (1974). https://doi.org/10.1007/BF01468505

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  • DOI: https://doi.org/10.1007/BF01468505

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