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European Archives of Oto-Rhino-Laryngology

, Volume 248, Issue 7, pp 425–427 | Cite as

Laryngeal papillomatosis with human papillomavirus DNA contracted by a laser surgeon

  • P. Hallmo
  • O. Naess
Case Reports

Summary

A 44-year-old laser surgeon presented with laryngeal papillomatosis. In situ DNA hybridization of tissue from these tumors revealed human papillomavirus DNA types 6 and 11. Past history revealed that the surgeon had given laser therapy to patients with anogenital condylomas, which are known to harbor the same viral types. These findings suggest that the papillomas in our patient may have been caused by inhaled virus particles present in the laser plume.

Key words

Laser vapor Human papillovirus DNA contamination Laser surgeon 

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References

  1. 1.
    Abramson AL, DiLorenzo TP, Steinberg BM (1990) Is papillomavirus detectable in the plume of laser-treated laryngeal papilloma? Arch Otolaryngol Head Neck Surg 116: 604–607PubMedGoogle Scholar
  2. 2.
    Alberti PW, Dykun R (1981) Adult laryngeal papillomata. J Otolaryngol 10: 463–470PubMedGoogle Scholar
  3. 3.
    Andre P, Orth G, Evenou P, Guillaume JC, Avril MF (1990) Risk of papillomavirus infection in carbon dioxide laser treatment of genital lesions. J Am Acad Dermtol 22: 131–132Google Scholar
  4. 4.
    Becker TM, Stone KM, Alexander ER (1987) Dramatic increase in consultation for genital warts in recent years. Obstet Gynecol Clin North Am 14: 389–396PubMedGoogle Scholar
  5. 5.
    Bender ME (1986) New concepts of condylomata acuminata in children. Arch Dermatol 122: 1121–1123PubMedGoogle Scholar
  6. 6.
    Cook TA, Brunschwig JP, Butel JS, Cohn AM, Goepfert H, Rawls WE (1973) Laryngeal papilloma: etiologic and therapeutic considerations. Ann Otol Rhinol Laryngol 82: 649–655PubMedGoogle Scholar
  7. 7.
    Duggan MA, Lim M, Gill MJ, Inoue M (1990) HPV DNA typing of adult-onset respiratory papillomatosis. Laryngoscope 100: 639–642PubMedGoogle Scholar
  8. 8.
    Ferenczy A, Bergeron C, Richart RM (1990) Human papillomavirus DNA in CO2 laser-generated plume of smoke and its consequences to the surgeon. Obstet Gynecol 75: 114–118PubMedGoogle Scholar
  9. 9.
    Garden JM, O'Banion MK, Shelnitz LS, Pinski KS, Bakus AD, Reichmann ME, Sundberg JP (1988) Papillomavirus in the vapor of carbon dioxide laser-treated verrucae. JAMA 259: 1199–1202PubMedGoogle Scholar
  10. 10.
    Gissmann L, Wolnik L, Ikenberg H, Koldovsky U, Schnürch HG, zur Hansen H (1983) Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers. Proc Natl Acad Sci USA 80: 560–563PubMedGoogle Scholar
  11. 11.
    Holinger PH, Johnston KC, Anison GC (1950) Papilloma of the larynx: a review of 109 cases with a preliminary report of aureomycin therapy. Ann Otol 59: 547–564Google Scholar
  12. 12.
    IEC standard 825 GenevaGoogle Scholar
  13. 13.
    Kleinsasser O, Oliviera E, Cruz G (1973) Übersichten: “Juvenile” und “adulte” Kehlkopfpapillome. HNO 21: 97–103PubMedGoogle Scholar
  14. 14.
    Lindeberg H, Øster S, Oxlund I, Elbrønd O (1986) Laryngeal papillomas: classification and course. Clin Otolaryngol 11: 423–429PubMedGoogle Scholar
  15. 15.
    Noble RC (1982) Sexually transmitted diseases. Guide to diagnosis and therapy. Medical Examination Publishing Co., Garden City, NY, pp 80–87Google Scholar
  16. 16.
    Quick CA, Krzyzek RA, Watts SL, Faras AJ (1980) Relationship between condylomata and laryngeal papillomata. Clinical and molecular virological evidence. Ann Otol Rhinol Laryngol 89: 467–471PubMedGoogle Scholar
  17. 17.
    Sawchuk WS, Felten RP (1989) Infectious potential of aerosolized particles (editorial). Arch Dermatol 125: 1689–1692PubMedGoogle Scholar
  18. 18.
    Sawchuk WS, Weber PJ, Lowy DR, Dzubow LM (1989) Infectious papillomavirus in the vapor of warts treated with carbon dioxide laser or electrocoagulation: detection and protection. J Am Acad Dermatol 21: 41–49PubMedGoogle Scholar
  19. 19.
    Schröder E (1989) Safety aspects. In: Riemann JF, Ell C (eds) Lasers in gastroenterology. Thieme, Stuttgart, pp 156–160Google Scholar
  20. 20.
    Sliney DH (1989) Laser safety in general surgery. In: Joffe SN (ed) Lasers in general surgery. Williams and Wilkins, Baltimore, pp 16–24Google Scholar
  21. 21.
    Strong MS, Vaughan CW, Cooperband SR, Healy GB, Clemente MAC (1976) Recurrent respiratory papillomatosis. Management with the CO2 laser. Ann Otol Rhinol Laryngol 85: 508–516PubMedGoogle Scholar
  22. 22.
    Syrjänen S, Partanen P, Mäntyjärvi R, Syrjänen K (1988) Sensitivity of in situ hybridization techniques using biotin- and 355-labeled human papillomavirus (HPV) DNA probes. J Virol Methods 19: 225–238PubMedGoogle Scholar
  23. 23.
    Teokharov BA (1969) Non-gonococcal infections of the female genitalia. Br J Vener Dis 45: 334–340PubMedGoogle Scholar
  24. 24.
    Terry RM, Lewis FA, Griffiths S, Wells M, Bird CC (1987) Demonstration of human papillomavirus types 6 and 11 in juvenile laryngeal papillomatosis by in-situ DNA hybridization. J Pathol 153: 245–248PubMedGoogle Scholar
  25. 25.
    Weiss MD, Kashima HK (1983) Tracheal involvement in laryngeal papillomatosis. Laryngoscope 93: 45–48PubMedGoogle Scholar
  26. 26.
    Wells M, Griffiths S, Lewis F, Bird CC (1987) Demonstration of human papillomavirus types in paraffin processed tissue from human anogenital lesions by in-situ DNA hybridisation. J Patholl 52: 77–82Google Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • P. Hallmo
    • 1
  • O. Naess
    • 2
  1. 1.Departments of OtorhinolaryngologyUllevaal City HospitalOsloNorway
  2. 2.Departments of PathologyUllevaal HospitalOsloNorway

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