Skip to main content
SpringerLink
Log in

The effect of amino acids on the rate of hydroxylation of cholesterol catalyzed by Mn and Fe porphyrinates

  • Chemistry of Natural Compounds and Bioorganic Chemistry
  • Published:
Russian Chemical Bulletin Aims and scope

Abstract

The rate and extent of hydroxylation of cholesterol catalyzed by Mn and Fe porphyrinates in the presence of NaBH4 increase with the addition of cysteine and histidine. This effect is more pronounced for cysteine. Leucine does not accelerate the process.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Cytochromes P-450 and B 5-Structure, Function and Interaction, Eds. D. Y. Cooper, O. Rosental, R. Snyger, and C. Witmer, Plenum Press, New York, 1975,58, 537 pp,

    Google Scholar 

  2. B. Meunier,Chem. Rev., 1992,92, 1411.

    Google Scholar 

  3. A. I. Samokhvalova, A. B. Solov'eva, A. L. Chugreev, I. A. Misurkin, and N. S. Enikolopyan,Dokl. Akad. Nauk SSSR, 1986,289, 2131 [Dokl. Chem., 1986,289 (Engl. Transl.)].

    Google Scholar 

  4. D. I. Metelitsa,Usp. Khim., 1981,51, 2019 [Russ, Chem. Rev., 1981,51 (Engl. Transl.)].

    Google Scholar 

  5. L. B. Karo and B. G. Harry,J. Am. Chem. Soc. 1993,115, 10382.

    Google Scholar 

  6. E. A. Lukashova, A. B. Solov'eva, E. A. Zheltukhina, L. K. Lubsandorzhieva, and R. P. Evstigneeva,A. Fiz. Ann., 1995,69, 1972 [Russ, J, Phys. Chem., 1995,69 (Engl. Transl.)].

    Google Scholar 

  7. K. A. Askarov, B. D. Berezin, and R. P. Evstigneeva, inPorfiriny: Struktura, Sintez, Svoistva [Porphyrins: Structure, Synthesis, Properties], Nauka, Moscow, 1985, 333 pp. (in Asian).

    Google Scholar 

  8. V. F. Tsepalov,Zavod, Lab., 1964, 101

  9. E A. Lukashova, A. B. Solov'eva, K. K. Pivnitsky, V. L. Mel'nikova, L. V. Karmilova, A. N. Kitaygorodskii, and N. S. Enikolopyan,Dokl, Akad. Nauk SSSR, 1987,296, 385 [Dokl. Chem., 1987,296 (Engl. Tranl.)],

    Google Scholar 

  10. A. B. Solov'eva, A. I. Sarnokhvalova, E. I. Karakozova, L. V. Karmilova, and N. S. Enikolopyan,Kinet. Katal., 1984,25, 1080 [Kinet. Catal., 1984,25 (Engl. Transl.)].

    Google Scholar 

  11. E. A. Lukashova, A. B. Solov'eva, G. Ya. Malinovsky, L. V. Karmilova, and N. S. Enikolopyan,Kinet. Katal. 1985,26, 56 [Kinet. Catal., 1985,26 (Engl. Transl.)].

    Google Scholar 

  12. N. S. Enikolopyan and A. B. Solov'eva,Zh. Fiz. Khim., 1988,62, 2289 [Russ. J. Phys. Chem., 1988,62 (Engl. Transl.)].

    Google Scholar 

  13. A. J. Gordon and R. A. Ford,The Chemists Companion, Wiley- Interscience, New York, 1972.

    Google Scholar 

  14. A. L. Chugreev, A, B. Solov'eva, A. I. Samokhvalova, and I. A. Misurkin,Teor. Eksp. Khim., 1987, 428 [Theor. Exp. Chem., 1987 (Engl. Transl.)].

Download references

Author information

Authors and Affiliations

  1. N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, 4 ul. Kosygina, 117977, Moscow, USSR

    A. B. Solov' eva, O. V. Cheremenskaya, N. V. Belkina & G. A. Zheltukhina

  2. M. V. Lomonosov Moscow State Academy of Fine Chemical Technology, 86 prosp. Vernadskogo, 117571, Moscow, USSR

    R. P. Evstigneeva

  3. Research Institute of Innovative Technology, 9-2 Kizugawadai, 619-02, Kyoto, Japan

    V. V. Borovkov

Authors
  1. A. B. Solov' eva
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. O. V. Cheremenskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. V. Belkina
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. P. Evstigneeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. A. Zheltukhina
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. V. V. Borovkov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 3000–3003, December, 1996.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Solov' eva, A.B., Cheremenskaya, O.V., Belkina, N.V. et al. The effect of amino acids on the rate of hydroxylation of cholesterol catalyzed by Mn and Fe porphyrinates. Russ Chem Bull 45, 2850–2853 (1996). https://doi.org/10.1007/BF01430659

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01430659

Key words

Search

Navigation