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Granulocytic sarcoma (chloroma) of the cerebellum and meninges

  • Case Report
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Summary

A 7-year-old boy, having had headache and vomiting for one month, was operated for a tumour in the left side of the posterior fossa. The tumour, weighing 52 g, infiltrated the dura mater, leptomeninges, and also, superficially, the left cerebellar hemisphere. The patient died five weeks after operation.

Light and electron microscopical examination revealed a granulocytic sarcoma (chloroma). Pre- and postoperative blood examinations, together with post-operative and autopsy bone marrow examinations, showed no sign of acute myelogenous leukaemia. This is the second reported case of primary intracranial chloroma with no preceding sign of acute myelogenous leukemia, and the first case with cerebellar infiltration.

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Author notes

  1. J. Nickels

    Present address: Patologian laitos, Haartmanink. 3, SF-00290, Helsinki 29, Finland

Authors and Affiliations

  1. Department of Pathology and Department of Neurosurgery, University of Helsinki, Finland

    J. Nickels, A. Koivuniemi & O. Heiskanen

Authors
  1. J. Nickels
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  2. A. Koivuniemi
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  3. O. Heiskanen
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Nickels, J., Koivuniemi, A. & Heiskanen, O. Granulocytic sarcoma (chloroma) of the cerebellum and meninges. Acta neurochir 46, 297–301 (1979). https://doi.org/10.1007/BF01430592

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  • DOI: https://doi.org/10.1007/BF01430592

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