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Population genetic study from the Zagreb area using 3 STR systems

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Abstract

Population genetic studies were carried out on Caucasians from north-west Croatia (Zagreb-area) using the short tandem repeat (STR) systems HumTHO1, HumVWA and HumACTBP2. After electrophoresis in PAG, 6 alleles could be identified for HumTHO1 in a sample size of 100 unrelated individuals and 7 alleles were found for VWA. For ACTBP2, 25 alleles have been identified. No significant deviations from Hardy-Weinberg equilibrium could be observed.

Zusammenfassung

Populationsstichproben nordwestkroatischer Kaukasier (Zagreb-Region) wurden mit den 3 Short tandem repeat (STR) Systemen HumTHO1, Hum-VWA und HumACTBP2 untersucht. Nach elektrophoretischer Auftrennung der Fragmente in PAG konnten 6 Allele für HumTHO1 in einer Bevölkerungsstichprobe von 100 nicht verwandten Personen und 7 Allele für Hum-VWA differenziert werden. Für ACTBP2 ließen sich 25 Allele unterscheiden. Eine signifikante Abweichung vom Hardy-Weinberg-Gleichgewicht wurde nicht festgestellt.

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References

  • Brinkmann B, Wiegand P (1994) Medicolegal implications of PCR based VNTRs. In: Proceedings from the Fourth International Symposium on Human Identification, Promega Corporation, Madison USA pp 149–160

    Google Scholar 

  • Brinkmann B, Rand S, Wiegand P (1991) Population and family data of RFLP's using selected single- and multi-locus systems. Int J Leg Med 104: 81–86

    Google Scholar 

  • Budowle B, Chakraborty R, Giusti AM, Eisenberg AJ, Allen RC (1991) Analysis of the variable number of tandem repeats locus DIS80 by the polymerase chain reaction followed by high resolution polyacrylamide gel electrophoresis. Am J Hum Genet 48: 137–144

    PubMed  Google Scholar 

  • Edwards A, Hammond HA, Jin L, Caskey CT, Chakraborty R (1992) Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups. Genomics 12: 241–253

    PubMed  Google Scholar 

  • Gill P, Kimpton CP, Sullivan K (1992) A rapid polymerase chain reaction method for identifying fixed specimens. Electrophoresis 13: 173–175

    PubMed  Google Scholar 

  • Kimpton CP, Walton A, Gill P (1992) A further tetranucleotide repeat polymorpism in the vWF gene. Hum Mol Genet 1: 28

    Google Scholar 

  • Kimpton CP, Gill P, Walton A, Urquhart A, Millican ES, Adams M (1993) Automated DNA profiling employing multiplex amplification of short tandem repeat loci. PCR Methods Appl 3: 13–22

    PubMed  Google Scholar 

  • Möller A, Brinkmann B (1994) Locus ACTBP2 (SE33) Sequencing data reveal considerable polymorphism. Int J Leg Med 106: 262–267

    Article  Google Scholar 

  • Möller A, Wiegand P, Grüschow C, Seuchter SA, Baur MP, Brinkmann B (1994) Population data and forensic efficiency values for the STR systems HumVWA, HumMBP and HumFABP. Int J Leg Med 106: 183–189

    Google Scholar 

  • Polymeropoulos MH, Rath DS, Xiao H, Merril CR (1992) Tetranucleotide repeat polymorphism at the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2). Nucleic Acids Res 20: 1432

    Google Scholar 

  • Rand S, Puers C, Skowasch K, Wiegand P, Budowle B, Brinkmann B (1992) Population genetics and forensic efficiency data of 4 AMPFLPs. Int J Leg Med 104: 329–333

    Google Scholar 

  • Wiegand P, Budowle B, Rand S, Brinkmann B (1993) Forensic validation of the STR systems SE33 and TC11. Int J Leg Med 105: 315–320

    Google Scholar 

Download references

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Kubat, M., Wiegand, P. & Brinkmann, B. Population genetic study from the Zagreb area using 3 STR systems. Int J Leg Med 107, 219–221 (1995). https://doi.org/10.1007/BF01428411

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  • DOI: https://doi.org/10.1007/BF01428411

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