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The use of Zenker's solution in linear craniectomy for craniosynostosis: Technical modification and reappraisal

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Summary

Regrowth of bone after craniectomy for craniosynostosis is still a problem, despite the advent of newer and extensive surgical techniques. A clinical study on 25 consecutive patients was undertaken to determine whether a modification of previous routines could retain the advantages of a tissue fixative, Zenker's solution, while eliminating the drawback of convulsive activity. After brief coagulation, Zenker's solution was sparingly applied to the durai surface for maximally one minute followed by copious irrigation of the surgical field. The results were satisfactory and postoperative complications unrelated to the fixative. The present procedure seems safe, effective, and easy to use.

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References

  1. Albright AL, Byrd RP (1981) Suture pathology in craniosynostosis. J Neurosurg 54: 384–387

    PubMed  Google Scholar 

  2. Anderson FM (1981) Treatment of coronal and metopic synostosis: 107 cases. Neurosurgery 8: 143–149

    PubMed  Google Scholar 

  3. Anderson FM, Geiger L (1965) Craniosynostosis. A survey of 204 cases. J Neurosurg 2: 229–240

    Google Scholar 

  4. Anderson FM, Johnson FL (1956) Craniosynostosis. A modification in surgical treatment. Surgery 40: 961–970

    PubMed  Google Scholar 

  5. Brenner H, Kraus H (1971) Craniosynostosis. Progr Neurol Surg 4: 429–469

    Google Scholar 

  6. Coppoletta JM, Wolbach SB (1933) Body length and organ weights of infants and children. A study of the body length and normal weights of the more important vital organs of the body between birth and twelve years of age. Am J Path 9: 55–70

    Google Scholar 

  7. David DJ, Poswillo D, Simpson D (1982) The craniosynostoses. Causes, natural history, and management. Springer, Berlin Heidelberg New York

    Google Scholar 

  8. Epstein N, Epstein F, Newman G (1982) Total vertex craniectomy for the treatment of scaphocephaly. Child's Brain 9: 309–316

    PubMed  Google Scholar 

  9. Gates GF, Dore EK (1975) Detection of craniosynostosis by bone scanning. Radiology 115: 665–671

    PubMed  Google Scholar 

  10. Goldstein FP, Kepes JJ, Brackett Jr, CE (1970) Experimental and clinical observations on the use of pericranium in inhibiting bone regrowth and fusion. J Neurosurg 32: 680–683

    PubMed  Google Scholar 

  11. Hoffman HJ, Mohr G (1976) Lateral canthal advancement of the supraorbital margin. J Neurosurg 45: 376–381

    PubMed  Google Scholar 

  12. Hope JW, Spitz EB, Slade HW (1955) The early recognition of premature cranial synostosis. Radiology 65: 183–193

    PubMed  Google Scholar 

  13. Ingraham FD, Matson DD, Alexander Jr, E (1948) Experimental observations in the treatment of craniosynostosis. Surgery 23: 252–268

    Google Scholar 

  14. Mabbutt LW, Kokich VG, Moffett BC, Loeser JD (1979) Subtotal neonatal calvariectomy. A radiographic and histological evaluation of calvarial and sutural redevelopmental in rabbits. J Neurosurg 51: 691–696

    PubMed  Google Scholar 

  15. Marlin AE, Brown Jr, WE, Huntington HW, Epstein F (1980) Effect of the dural application of Zenker's solution on the feline brain. Neurosurgery 6: 45–48

    PubMed  Google Scholar 

  16. Marsh JL, Schwartz HG (1983) The surgical correction of coronal and metopic craniosynostosis. J Neurosurg 59: 245–251

    PubMed  Google Scholar 

  17. McComb JG, Withers GJ, Davis RL (1981) Cortical damage from Zenker's solution applied to the dura mater. Neurosurgery 8: 68–71

    PubMed  Google Scholar 

  18. McLaurin RL, Matson DD (1952) Importance of early surgical treatment of craniosynostosis. Pediatrics 10: 637–652

    PubMed  Google Scholar 

  19. Montaut J, Stricker M (1977) Les dysmorphies cranio-faciales. Les synostoses prématurées (craniosténoses et faciosténoses). Neuro-chirurgie [Suppl 2] 23: 1–299

    Google Scholar 

  20. Muakkassa KF, Hoffman HJ, Hinton DR, Hendrick EB, Humphreys RP, Ash J (1984) Lambdoid Synostosis. Part 2: Review of cases managed at The Hospital for Sick Children, 1972–1982. J Neurosurg 61: 340–347

    PubMed  Google Scholar 

  21. Norwood CW, Alexander Jr, E, Davis CH, Kelly Jr, DL (1974) Recurrent and multiple suture closures after craniectomy for craniosynostosis. J Neurosurg 41: 715–719

    PubMed  Google Scholar 

  22. Pawl RP, Sugar O (1972) Zenker's solution in the surgical treatment of craniosynostosis. J Neurosurg 36: 604–607

    PubMed  Google Scholar 

  23. Samra KA, Sorour O (1968) Bilateral flap operation for craniosynostosis. J Neurosurg 29: 591–596

    PubMed  Google Scholar 

  24. Scammon RE, Dunn HL (1922–1923) Empirical formulae for the postnatal growth of the human brain and its major divisions. Proc Soc Exp Biol Med 20: 114–117

    Google Scholar 

  25. Shillito Jr, J, Matsom, DD (1968) Craniosynostosis: A review of 519 surgical patients. Pediatrics 41: 829–853

    PubMed  Google Scholar 

  26. Sirola K (1960) Regeneration of defects in the calvaria. An experimental study. Ann Med Exp Biol Fenn 38: [Suppl 2] 1–87

    Google Scholar 

  27. Sorour O (1961) The four-flap operation. A new operation for treatment of craniosynostosis. J Neurosurg 18: 86–90

    Google Scholar 

  28. Stein SC, Schut L (1977) Management of scaphocephaly. Surg Neurol 7: 153–155

    PubMed  Google Scholar 

  29. Sugar O, Comments; McCombet al. (1981) Cortical damage from Zenker's solution applied to the dura mater. Neurosurgery 8: 71

    Google Scholar 

  30. Van der Werf AJM (1977) Craniosynostosis. A new operative technique. Clin Neurol Neurosurg 80: 70–81

    PubMed  Google Scholar 

  31. Venes JL, Sayers MP (1976) Sagittal synostectomy. Technical note. J Neurosurg 44: 390–392

    PubMed  Google Scholar 

  32. Vollmer DG, Jane JA, Park TS, Persing JA (1984) Variants of sagittal synostosis: Strategies for surgical correction. J Neurosurg 61: 557–562

    PubMed  Google Scholar 

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Author notes

  1. L. Brandt

    Present address: Department of Neurosurgery, University of Lund, Sweden

Authors and Affiliations

  1. Department of Neurosurgery, University of Lund, Sweden

    B. Ljunggren

  2. Department of Anatomy, University of Lund, Sweden

    P. Alberius

Authors
  1. L. Brandt
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  2. P. Alberius
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  3. B. Ljunggren
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Brandt, L., Alberius, P. & Ljunggren, B. The use of Zenker's solution in linear craniectomy for craniosynostosis: Technical modification and reappraisal. Acta neurochir 83, 67–70 (1986). https://doi.org/10.1007/BF01420511

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  • DOI: https://doi.org/10.1007/BF01420511

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