Skip to main content

Advertisement

Log in

Transnasal surgery in the treatment of craniopharyngiomas

  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Summary

The results of transnasal-transsphenoidal surgery in 31 patients with craniopharyngioma are evaluated. To assess the value of transnasal surgery in cases with visual impairment, the results are compared to cases operated transcranially. There was only one death occurred on the 5th postoperative day. Two patients developed rhinoliquorrhoea, and one a transient oculomotor palsy. Recurrences leading to re-operation occurred frequently after mere cyst aspiration and only once after subtotal tumour removal. Normal glandotrope functions of the hypophysis were preserved in 75%, disturbed functions were normalized in 19% of primary transnasal surgery. Visual disturbances were normalized or improved in 94% cases after transnasal surgery, whereas an improvement was observed in only 65% after transcranial surgery. A deterioration never appeared after transnasal surgery, but in 26% after transcranial operations.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Andler W, Roosen K, Clar HE (1979) Pre- and postoperative evaluation of hypothalamo-pituitary function in children with craniopharyngiomas. Acta Neurochir (Wien) 45: 287–299

    Google Scholar 

  2. Artero JMC, Crespo JV, Zabalgoitia GB (1984) Status of vision following surgical treatment of craniopharyngiomas. Acta Neurochir (Wien) 73: 165–177

    Google Scholar 

  3. Baum Newman C, Levine LS, New MI (1981) Endocrine function in children with intrasellar and suprasellar neoplasms. Am J Dis Child 135: 259–262

    PubMed  Google Scholar 

  4. Citrić IS, Cozzens JW (1980) Craniopharyngiomas: Transsphenoidal method of approachfor the virtuoso only? In: Clinical neurosurgery (Proceedings of the congress of neurological surgeons). Williams & Wilkins, Baltimore London, pp 169–187

    Google Scholar 

  5. Garcia-Uria J (1978) Surgical experience with craniopharyngioma in adults. Surg Neurol 9: 11–14

    PubMed  Google Scholar 

  6. Grant DB, Lyen K (1982) Hypopituitarism after surgery for craniopharyngioma. Childs Brain 9: 201–204

    PubMed  Google Scholar 

  7. Grisoli F, Vincentelli F, Farnarier P, Gondim-Oliveira J, Vigouroux RP (1982) Trans-sphenoidal microsurgery in the management of non-pituitary tumours of the sella turcica. In: Brock M (ed) Modern neurosurgery 1. Springer, Berlin Heidelberg New York, pp 193–204

    Google Scholar 

  8. Hamlin H (1967) Discussion: The treatment of craniopharyngiomas (Leksell L, Backlund E-O). Acta Neurol Scand. 43: 240

    Google Scholar 

  9. Hardy J, Vezina JL (1976) Transsphenoidal neurosurgery of intracranial neoplasm. In: Thompson RA, Green JR (eds) Advances in neurology, vol 15. Raven Press, New York, pp 261–274

    Google Scholar 

  10. Hoffman HJ, Hendrick EB, Humphreys RP, Buncic JR, Armstrong DL, Jenkin RDT (1977) Management of craniopharyngioma in children. J Neurosurg 47: 218–227

    PubMed  Google Scholar 

  11. Konovalov AN (1981) Operative management of craniopharyngiomas. In: Krayenbühl H,et al. (eds) Advances and technical standards in neurosurgery, vol 8. Springer, Wien New York, pp 281–318

    Google Scholar 

  12. Laws ER, Trautmann JC, Hollenhorst Jr, RW (1977) Transsphenoidal decompression of the optic nerve and chiasm. Visual results in 62 patients. J Neurosurg 46: 717–722

    PubMed  Google Scholar 

  13. Laws ER (1980) Transsphenoidal microsurgery in the management of craniopharyngioma. J Neurosurg 52: 661–666

    PubMed  Google Scholar 

  14. Lindgren E, di Chiro G (1951) Suprasellar tumours with calcification. Acta Radiol 36: 173–195

    PubMed  Google Scholar 

  15. Lüdecke DK (1982) Behandlung der Hypophysentumoren. In: Nieschlag E (ed) Endokrinologische Therapie in der Reproduktionsmedizin. Deutscher ärzte-Verlag, pp 89–119

  16. Lyen KR, Grant DB (1982) Endocrine function, morbidity, and mortality after surgery for craniopharyngioma. Arch Dis Child 57: 837–841

    PubMed  Google Scholar 

  17. Northfield DWC (1957) Rathke-pouch tumours. Brain 80: 293–311

    PubMed  Google Scholar 

  18. Pertuiset B, Craniopharyngiomas. In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology, vol 18. North-Holland Publishing Company, Oxford, American Elsevier Publishing Co, Inc, New York, pp 531–572

  19. Raimondi AJ, Rougerie J (1983) A critical review of personal experiences with craniopharyngioma: Clinical history, surgical technique and operative results. In: Raimondi AJ (ed) Concepts in pediatric neurosurgery 3. S. Karger, Basel München Paris London New York Tokyo Sydney, pp 1–34

    Google Scholar 

  20. Resch R, Haas H, Schwarz S, Mayr U, Twerdy K, Hüttenberger H (1981) Kraniopharyngeom. Erfahrungen mit der Kombination von Operation und Bestrahlung sowie Probleme der hormonellen Substitution. Dtsch Med Wochenschr 106: 1502–1508

    PubMed  Google Scholar 

  21. Rougerie J (1974) Intrasellar and suprasellar tumors of the infant and adolescent. In: Bushe K-A, Spoerri O, Shaw J (eds) Progress in pediatric neurosurgery. Hippokrates, Stuttgart, pp 34–45

    Google Scholar 

  22. Shapiro K, Till K, Grant DN (1979) Craniopharyngiomas in childhood. A rational approach to treatment. J Neurosurg 50: 617–623

    PubMed  Google Scholar 

  23. Stahnke N, Grubel G, Lagenstein I, Willig RP (1984) Long-term follow-up of children with craniopharyngioma. Eur J Pediatr 142: 179–185

    PubMed  Google Scholar 

  24. Takahashi T, Fujii H, Toba Y, Isayama Y, Tamaki N, Matsumoto S (1983) Craniopharyngioma—analysis of surgical procedure. Jpn J Ophthalmol 27: 380–386

    PubMed  Google Scholar 

  25. Thomsett MJ, Conte FA, Kaplan SL, Grumbach MM (1980) Endocrine and neurologic outcome in childhood craniopharyngioma: review of effect of treatment in 42 patients. J Pediat 97: 728–735

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Dedicated to Prof. Dr. Friedrich Loew on the occasion of his 65th birthday and the 25th anniversary of the Homburg Neurosurgical University Clinic, which has been founded and built up by him.

Rights and permissions

Reprints and permissions

About this article

Cite this article

König, A., Lüdecke, D.K. & Herrmann, H.D. Transnasal surgery in the treatment of craniopharyngiomas. Acta neurochir 83, 1–7 (1986). https://doi.org/10.1007/BF01420500

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01420500

Keywords

Navigation