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Polyurethane vascular prostheses in pigs

  • Polymer Science
  • Published:
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Abstract

Microporous, compliant vascular prostheses made from segmented polyurethanes of various molecular stability, have been implanted in the infrarenal aorta of young pigs. Prostheses prepared from a hydrolytically suble polyetherurethane showed a limited patency up to 1 month. Composite prostheses with the wall made from a hydrolytically stable polyurethane and the lumen side prepared from a degradable polyurethane, were patent up to one year. A degradable layer of this composite prosthesis induced the growth of a neo-artery. Prostheses prepared from a degradable polyurethane alone, were substituted within 4 months with a functional neo-artery.

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Author notes

  1. S. Gogolewski

    Present address: Medinvent SA, Lausanne, Switzerland

Authors and Affiliations

  1. University of Bologna, Italy

    G. Galletti & G. Ussia

Authors
  1. S. Gogolewski
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  2. G. Galletti
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  3. G. Ussia
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Additional information

Presented in part at the 17th International Biomaterials Symposium, San Diego, California, April 1985.

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Gogolewski, S., Galletti, G. & Ussia, G. Polyurethane vascular prostheses in pigs. Colloid & Polymer Sci 265, 774–778 (1987). https://doi.org/10.1007/BF01418452

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  • DOI: https://doi.org/10.1007/BF01418452

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