Summary
This is a case of intracranial sarcoma which was recognized 23 years after irradiation therapy for pituitary adenoma. Four operations were performed because of recurrences with a short interval between each operation. Immunohistochemically, the tumour cells were stained for smooth muscle actin, human muscle actin and vimentin. It was verified as a leiomyosarcoma. This report is the first case of intracranial leiomyosarcoma associated with radiation therapy in pituitary adenoma.
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Niwa, J., Hashi, K. & Minase, T. Radiation induced intracranial leiomyosarcoma: Its histopathological features. Acta neurochir 138, 1470–1471 (1996). https://doi.org/10.1007/BF01411129
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DOI: https://doi.org/10.1007/BF01411129