Summary
A prospective survey of wound infection in a continuous series of 357 patients undergoing operations at a neurosurgical unit was made. The incidence of wound infection was 4.7 percent. Causative organisms were isolated in only 29.4 percent of the clinically infected cases. The type of suture material used did not affect the infection rate and neither did the coincidental use of steroids in the high doses employed in neurosurgical practice.
Re-exploration does not carry an increased risk of infection. Use of systemic or topical antibiotics or both was not found to confer any protection against wound infection.
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References
Cairns, H., Bacterial infection during intracranial operation. 1939.
Cochran, W. G., Some methods of strengthening the common x2 tests. Biometrics10 (1954), 417–451.
Cushing, H., Concerning the results of operations for brain tumours. J. Amer. med. Ass.64 (1915), 189–195.
—, Surgery of the head. In: Surgery, its principles and practice (Keen, W. W., ed.). Philadelphia: W. B. Saunders Co. 1908.
—, Tumours of nervus acusticus and the syndrome of the cerebellopontine angle, p. 296. Philadelphia: W. B. Saunders Co. 1917.
—, Experiences with the cerebellar astrocytomas. A critical review of seventy six cases. Surg. Gyn. Obstet.52 (1931), 129–204.
—, Eisenhardt, L., Meningiomas: their classification, regional behaviour, life history, and surgical end results, p. 785. Springfield, Ill.: Ch. C Thomas. 1938.
Douglas, D. M., Wounds and their problems. J. R. Coll. Surg.20 (1975), 77–95.
Eiselsberg, A. von, Ranzie, E., Über die chirurgische Behandlung der Hirn- und Rückenmarkstumoren. Arch. Klin. Chir.102 (1913), 309–468.
Forbes, G. B., Staphylococcal infection operation wounds with special reference to topical antibiotic prophylaxis. Lancet2 (1961), 505–509.
Forster, J. C., Suture materials and their use. Brit. J. Hosp. Med.8, No. 5 (1972), 578–592.
Lowbery, E. J. L.et al., Aseptic methods in the operating suite. Lancet1 (1968), 706–709, 763–768, 831–837.
Pennybacker, J. B., Taylor, M., Cairns, H., Penicillin in the prevention of infection during operations on the brain and spinal cord. Lancet2 (1947), 159–162.
Public Health, Laboratory Report, Incidence of surgical wound infection in England and Wales. Lancet2 (1960), 659–663.
Tooth, H. T., The treatment of tumours of the brain and the indication for operation. Trans. Imp. Cong. Med. Lond.8 (1913), 203–299.
Thornton, G. F., Fekety, F. R., Cluff, L., Studies of the epidemiology of staphylococcal infection. VIII Seasonal variation. New Eng. J. Med.271 (1964), 1333–1337.
Wright, R. C., Burke, J. F., A survey of possible etiological agents in post operative craniotomy infections. J. Neurosurgery25 (1966), 125–132.
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Quadery, L.A., Medlery, A.V. & Miles, J. Factors affecting the incidence of wound infection in neurosurgery. Acta neurochir 39, 133–141 (1977). https://doi.org/10.1007/BF01406722
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DOI: https://doi.org/10.1007/BF01406722