Summary
We present the results of a study comparing two groups of patients who underwent neurosurgical operations, one pretreated with Ampicillin (184) and the other not (193), in comparable timespans. The results of this study argue for a beneficial action of Ampicillin prophylaxis on neurosurgical infections. A brief discussion of the appropriate literature is given.
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References
Blomstedt GC (1985) Infections in neurosurgery: a retrospective study of 1143 patients and 1517 operations. Acta Neurochir (Wien) 78: 81–90
Geraghty J, Feely M (1984) Antibiotic prophylaxis in neurosurgery. A randomized controlled trial. J Neurosurg 60: 724–726
Haines SJ (1980) Systematic antibiotic prophylaxis in neurological surgery. Neurosurgery 6: 355–361
Haines SJ, Goodman ML (1982) Antibiotic prophylaxis of postoperative neurosurgical wound infection. J Neurosurg 56: 103–105
Horwitz NH, Curtin JA (1975) Prophylactic antibiotics and wound infections following laminectomy for lumbar disc herniation. A retrospective study. J Neurosurg 43: 727–731
Klastersky J, Kahan-Coppens L, Brihaye J (1979) Infections in Neurosurgery. In: Krayenbühl H,et al (eds) Advances and technical standards in neurosurgery, vol 6. Springer, Wien New York, pp 39–54
Malis LI (1979) Prevention of neurosurgical infection by intraoperative antibiotics. Neurosurgery 5: 339–343
Quaderly LA, Medlery AV, Miles J (1977) Factors affecting the incidence of wound infection in neurosurgery. Acta Neurochir (Wien) 39: 133–141
Quartey GRC, Polyzoidis K (1981) Intraoperative antibiotic prophylaxis in neurosurgery: a clinical study. Neurosurgery 8: 669–671
Wright RL (1966) A survey of possible etiologic agents in postoperative craniotomy infections. J Neurosurg 25: 125–132
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Reale, F., Biancotti, R., De Falco, D. et al. Antibiotic prophylaxis in neurosurgery. Acta neurochir 86, 75–78 (1987). https://doi.org/10.1007/BF01402287
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DOI: https://doi.org/10.1007/BF01402287