Summary
A case is reported of a 21 month old boy from whom a 357 g ependymona was removed. Postoperatively, radiation therapy (Co60) was administered, and the central dosage was estimated to be 4,350 r given over 46 days. Seven and a half years later craniotomy was again performed because of a supposed recurrence. However, a meningeal sarcoma weighing 370 g was found.
Tumour induction by radiotherapy is discussed on the basis of published reports, and the need of estimating tumour dose in relationship to the age of the patient is stressed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Beller, A. J., Feinsod, M., Sahar, A., The possible relationship between small dose irradiation to the scalp and intracranial meningiomas. Neurochirurgia4 (1972), 135–143.
Feiring, E. H., Foer, W. H., Meningioma following radium therapy. J. Neuro- surg.29 (1968), 192–194.
Fokes, E. C., Earle, K. M., Ependymomas: Clinical and pathological aspects, J. Neurosurg.30 (1969), 585–594.
Li, F. P., Cassady, J. R., Jaffe, N., Risk of second tumours in survivors of childhood cancer. Cancer35 (1975), 1230–1235.
Mann, I., Yates, P. C., Ainslie, J. P., Unusual case of double primary orbital tumour. Brit. J. Ophthal.37 (1953), 758–762.
Modan, B., Mart, H., Baidatz, D., Steinitz, R., Levin, S. G., Radiation-induced head and neck tumours. The LancetI (1974), 277–279.
Munk, J., Peyser, E., Gruszkiewicz, J., Radiation induced intracranial meningiomas. Clin. Radiol.20 (1969), 90–94.
Noetzli, M., Malamud, N., Postirradiation fibrosarcoma of the brain. Cancer15 (1962), 617–622.
Norwood, C. W., Kelly, D. L., Jr., Davis, C. H., Jr., Alexander, E., Jr., Irradiation-induced mesodermal tumours of the central nervous system: Report of two meningiomas following X-ray treatment for gliomas. Surg, Neurol.2 (1974), 161–164.
Onoyama, Y., Abe, M., Takahashi, M., Yabumoto, Eizo, Sakamoto, T., Radiation therapy of brain tumours in children. Radiology115 (1975), 687–693.
Veraguth, P., Les séquelles de la radiothérapie chez l'enfant. Radiol. clin. biol.41 (1972), 285–297.
Waltz, T. A., Brownell, B., Sarcoma: A possible late result of effectiveradiation therapy for pituitary adenoma. J. Neurosurg.24 (1966), 901–907.
Zülch, K. J., Biologie und Pathologie der Hirngeschwülste. In: Handbuch der Neurochirurgie, Vol. 3, p. 492 (Olivecrona, H., Tönnis, W., eds.). Berlin-Göttingen-Heidelberg: Springer. 1956.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bojsen-Møller, M., Knudsen, V. Radiation-induced meningeal sarcoma. Acta neurochir 37, 147–152 (1977). https://doi.org/10.1007/BF01401933
Issue Date:
DOI: https://doi.org/10.1007/BF01401933