Skip to main content

Advertisement

Log in

Statistical analysis of factors affecting survival after glioblastoma multiforme

  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Summary

Statistical evaluation of 71 cases (adults) of histologically confirmed supratentorial surgically treated glioblastoma multiforme seen during the period 1958 to 1973 revealed that the state of calcification as determined by roentgenography and the histological appearance of the neoplasm appeared to have a relationship with the postoperative period of survival. Postoperative adjuvant treatment, location of the neoplasm, duration of preoperative symptoms, patient's age at onset, preoperative condition, and cystic formation in the neoplasm also appeared to have a relationship, although it was slight.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Abramson, N., Raben, M., Cavanaugh, P. J., Brain tumours in children: Analysis of 136 cases. Radiology112 (1974), 669–672.

    PubMed  Google Scholar 

  • Busch, E., Christensen, E., The three types of glioblastoma. J. Neurosurg.4 (1947), 200–220.

    Google Scholar 

  • Elvidge, A. R., Barone, B. M., Long-term postoperative survival in two case of glioblastoma multiforme. J. Neurosurg.22 (1965), 382–386.

    PubMed  Google Scholar 

  • Frankel, S. A., German, W. J., Glioblastoma multiforme: Review of 219 cases with regard to natural history, pathology, diagnostic methods and treatment. J. Neurosurg.15 (1958), 489–503.

    PubMed  Google Scholar 

  • Hara, M., Maeda, T., Takeuchi, K., Kitamura, M., Biochemical analysis of cyst fluid of brain tumour (in Japanese). Brain and Nerve26 (1974), 1075–1082.

    Google Scholar 

  • Hildebrand, J., Brihaye, J., Malignant gliomas: Prognostic factors and criteria of response. In: Cancer Therapy; Prognostic Factors and Criteria of Response, pp. 309–318. Edited by M. J. Staquet. New York: Raven Press. 1975.

    Google Scholar 

  • Hitchcock, E., Sato, F., Treatment of malignant gliomata. J. Neurosurg.21 (1964). 497–505.

    PubMed  Google Scholar 

  • Jelsma, R., Bucy, P. C., The treatment of glioblastoma multiforme of the brain. J. Neurosurg.27 (1967), 388–400.

    PubMed  Google Scholar 

  • — —, Glioblastoma multiforme: Its treatment and some factors affecting survival. Neurology20 (1969), 161–171.

    Google Scholar 

  • Netsky, M. G., August, B., Fowler, W., The longevity of patients with glioblastoma multiforme. J. Neurosurg.7 (1950), 261–269.

    PubMed  Google Scholar 

  • Pool, J. L., The management of recurrent gliomas. Clin. Neurosurg.15 (1968), 265–287.

    PubMed  Google Scholar 

  • Roth, J. G., Elvidge, A. R., Glioblastoma multiforme: A clinical survey. J. Neurosurg.17 (1960), 736–750.

    PubMed  Google Scholar 

  • Sachs, E., Treatment of glioblastoma with radium. J. Neurosurg.11 (1954), 119–121.

    PubMed  Google Scholar 

  • Schröder, R., Müller, W., Bonis, G., Vorreith, M., Statistische Beiträge zum Grading der Gliome. III. Astrozytome und Oligodendrogliome. Acta Neurochir. (Wien)23 (1970), 1–29.

    Google Scholar 

  • Shuangshotic, S., Jangchai, P., Special features of intracranial glioblastoma multiforme in Thailand. Far East Medical Journal5 (1969), 29–31.

    Google Scholar 

  • Stage, W. S., Stein, J., Treatment of malignant astrocytomas. Amer. J. Roentgenol.120 (1974), 7–18.

    PubMed  Google Scholar 

  • Takeuchi, K., Yahagi, Y., Nagai, M., Mizutani, H., Sato, F., Chigasaki, H., Asano, K., Uei, I., Morimoto, W., Chemotherapy of brain tumour by localized cerebral perfusion (5th report). Neurologia medico-chirurgica6 (1964), 122–123.

    Google Scholar 

  • —, Atsuchi, M., Chemotherapy of brain tumours by continuous intracarotid infusion of 5-Fluorouasil. In: Progress in Antimicrobial and Anticancer Chemotherapy, Vol. II., pp. 226–230. Edited by H. Umezawa. Tokyo: University of Tokyo Press. 1970.

    Google Scholar 

  • Takeuchi, K., Sueyoshi, S., Hara, M., Ogihara, R., Treatment of brain tumours with bleomycin. In: Progress in Chemotherapy, Vol. III., pp. 918–924. Edited by G. K. Daikos. Athens: Hellenic Society for Chemotherapy. 1974.

    Google Scholar 

  • —, A clinical trial of intravenous bleomycin in the treatment of brain tumours. Internat. J. Clin. Pharmacol.12 (1975), 419–426.

    Google Scholar 

  • Tanaka, Y., Takeuchi, K., Maeda, T., Calcification in gliomas: First report with special reference to roentgenological calcification (in Japanese). Neurol. Surg. (Tokyo),3 (1975), 219–225.

    Google Scholar 

  • Taveras, J. M., Thompson, H. G., Jr., Pool, J. L., Should we treat glioblastoma multiforme. Amer. J. Roentgenol.87 (1962), 473–479.

    PubMed  Google Scholar 

  • Weir, B., The relative significance of factors affecting postoperative survival in astrocytoma, grades 3 and 4. J. Neurosurg.38 (1973), 448–452.

    PubMed  Google Scholar 

  • Wüllenweber, R., Kuhlendahl, H., Miltz, H., Grunert, V., Sunder-Plassmann, M., Astrocytomas and glioblastomas: A comparative review of 2,500 cases. Excerpta Medica International Congress Series No.293 (1973), 36–37.

    Google Scholar 

  • Yamashita, J., Gillingham, F. J., The effect of radiotherapy for glioblastoma: A review of 516 cases (in Japanese). Neurol. Surg. (Tokyo),3 (1975), 329–336.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Takeuchi, K., Hoshino, K. Statistical analysis of factors affecting survival after glioblastoma multiforme. Acta neurochir 37, 57–73 (1977). https://doi.org/10.1007/BF01401926

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01401926

Keywords

Navigation