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Changes in activity of Krebs and glyoxylate cycles during biosynthesis of agroclavine and elymoclavine

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Summary

In a submerged Claviceps purpurea culture decrease of the Krebs cycle (KC) activity and rise of that of glyoxylate cycle (GC) preceded the intensive alkaloid synthesis. Pyruvate entered the cell mainly via GC. Some KC acids participated in the lifting of catabolite repression to increase the alkaloid yield significantly.

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References

  • Cook R. A., and Sanwal B.D. In: Methods in Enzymology. Vol. XIII. Eds. S.P. Colowick, and N.O. Kaplan. Academic Press Inc., New York 1969, p.22.

    Google Scholar 

  • Davies D.D. Ibid., p.148

    Google Scholar 

  • Dobrogosz W. J. (1966). J. Bacteriol. 91: 2263–2269

    PubMed  Google Scholar 

  • Flavell R.B., and Fincham J.R.S. (1968). J. Bacteriol. 95: 1063–1068

    PubMed  Google Scholar 

  • Lane M.D., Chang H.G., and Miller R.S. In: Methods in Enzymology. Vol. XIII. Eds. S.P. Colowick, and N.O. Kaplan, Academic Press Inc., New York 1969, p.270.

    Google Scholar 

  • Maeba P., and Sanwal B.D. Ibid., p. 283

    Google Scholar 

  • McFadden B.A. Ibid., p. 163

    Google Scholar 

  • Řeháček Z., Sajdl P., Kozová J., Malik K.A., and Řicicová A. (1971). Appl. Microbiol. 22: 949–956.

    PubMed  Google Scholar 

  • Schröder P. (1978). Biochem. Physiol. Pflanzen (in press).

  • Seubert W., and Weicker H. In: Methods in Enzymology. Vol. XIII. Eds. S.P. Colowick, and N.O. Kaplan, Academic Press Inc., New York 1969, p. 258.

    Google Scholar 

  • Veeger C., der Vartanien D.V., and Zeylemaker W.P. Ibid.In:, p. 81.

    Google Scholar 

  • Weitzman P.D.J. Ibid. In:, p. 22.

    Google Scholar 

  • Wurst M., Flieger M., and Řeháček Z. (1978). J. Chromatogr. 150: 477–483.

    Google Scholar 

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Authors and Affiliations

  1. Department of Biogenesis of Natural Substances, Institute of Microbiology, Czechoslovak Academy of Sciences, 142 20, Praha 4, Budejovická 1083, Czechoslovakia

    Z. Řeháček & P. Sajdl

Authors
  1. Z. Řeháček
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  2. P. Sajdl
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Řeháček, Z., Sajdl, P. Changes in activity of Krebs and glyoxylate cycles during biosynthesis of agroclavine and elymoclavine. Biotechnol Lett 1, 53–57 (1979). https://doi.org/10.1007/BF01395791

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