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Asymmetric syntheses of pipecolic acid and derivatives

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Summary

Results in the field of asymmetric synthesis of pipecolic acid derivatives are reviewed. Three sections describe the asymmetric syntheses of the title compounds (i) from the chiral pool (α-amino acids or carbohydrates) (ii) using a chiral auxiliary either derived from terpenes,α-amino acids, tartaric acid, an amine orβ-amino alcohols (iii) by means of asymmetric catalysis.

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  1. Laboratoire de synthèse asymétrique, Université Paris 6, 4, place Jussieu, F-75005, Paris, France

    François Couty

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Couty, F. Asymmetric syntheses of pipecolic acid and derivatives. Amino Acids 16, 297–320 (1999). https://doi.org/10.1007/BF01388174

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