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Properties of temperature-sensitive mutants of parainfluenza virus type 3 selected during the course of persistent infection

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Summary

We investigated properties of thets mutants that were selected during the course of persistent infection of Vero cells by parainfluenza virus type 3. The mutants demonstrated leakiness when infecting cells at high MOI and interfered with the growth of wild type virus, apparently by inhibiting a step prior to RNA synthesis.

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References

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Authors and Affiliations

  1. Department of Pediatrics, The Mount Sinai School of Medicine, New York, New York, USA

    S. Asamura & D. S. Hodes

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  1. S. Asamura
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  2. D. S. Hodes
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Asamura, S., Hodes, D.S. Properties of temperature-sensitive mutants of parainfluenza virus type 3 selected during the course of persistent infection. Archives of Virology 84, 291–296 (1985). https://doi.org/10.1007/BF01378982

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  • DOI: https://doi.org/10.1007/BF01378982

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