Abstract
The toxic and antiarrhythmic activities of diterpene alkaloids fromAconitum zeravschanicum and their synthetic analogs have been investigated. It has been established that, in the series of compounds studied, activity and toxicity depend on the type of skeleton, the nature and positions of substituents, and the basicity of the nitrogen atom.
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Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 384–387, May–June, 1996. Original article submitted February 26, 1996.
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Salimov, B.T., Kuzibaeva, Z.K. & Dihakhangirov, F.N. Study of structure-activity relationships in a series of alkaloids ofAconitum zeravschanicum and their analogs. Chem Nat Compd 32, 366–368 (1996). https://doi.org/10.1007/BF01372341
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DOI: https://doi.org/10.1007/BF01372341