Abstract
Celiac disease was diagnosed in one patient with variegate porphyria, and dermatitis herpetiformis in two patients, one with acute intermittent porphyria and the other with erythropoietic protoporphyria. The probability that celiac disease or dermatitis herpetiformis should occur in three patients with porphyria in Finland is less than 0.2%. Neither a consistent HLA pattern nor any other explanation can be offered for the association between these diseases.
Similar content being viewed by others
References
Alexander JO'D: Dermatitis herpetiformis.In Major Problems in Dermatology, Vol. 4, A Rook (ed). London, WB Saunders, 1975, p 259
Katz SI, Strober W: The pathogenesis of dermatitis herpetiformis. J Invest Dermatol 70:63–75, 1978
Cooper BT, Holmes GKT, Cooke WT: Coeliac disease and immunological disorders. Br Med J 1:537–539, 1978
Scott BB, Losowsky MS: Coeliac disease: A cause of various associated diseases. Lancet 2:956–957, 1975
Tschudy DP: Porphyrin metabolism and the porphyrias, Chapter 12.In Duncan's Diseases of Metabolism, 7th ed, PK Bondy, LE Rosenberg (eds). Philadelphia, Saunders 1974, p 811
Cram DL, Epstein JH, Tuffanelli DL: Lupus erythematosus in porphyria. Arch Dermatol 108:779–784, 1973
Stein JA, Tschudy DP: Acute intermittent porphyria. A clinical and biochemical study of 46 patients. Medicine 49:1–16, 1970
Mustajoki, P, Koskelo P: Hereditary hepatic porphyrias in Finland. Acta Med Scand 200:171–178, 1976
Reunala T: Gluten-free diet in dermatitis herpetiformis. II. Morphological and immunological findings in the skin and small intestine of 12 patients and matched controls. Br J Dermatol 98:69–78, 1978
Reunala T, Lokki J: Dermatitis herpetiformis in Finland. Acta Derm Venereol 58:505–510, 1978
Mustajoki P: Variegate porphyria. Twelve years experience in Finland. Q J Med 49:191–203, 1980
Hopsu-Havu VK, Terho PE, Hollmén T: Erythropoietic protoporphyria. The first case in Finland. Ann Clin Res 5:181–185, 1973
Strober W, Falchuk ZM, Rogentine GN, Nelson DL, Klaeveman HL: The pathogenesis of gluten-sensitive enteropathy. Ann Intern Med 83:242–256, 1975
Epstein JH, Tuffanelli DL, Epstein WL: Cutaneous changes in porphyrias. Arch Dermatol 107:689–698, 1973
Teuber J, Druschky F, Franzke W, Baenkler HW: HLA frequencies in intermittent acute porphyria. Int Arch Allergy Appl Immunol 54:473–474, 1977
Tongio MM, Mayer S, Hauptmann G, North ML, Koehl C, Abecassis J, Mandel P, Wertenschlag J: Lack of linkage between acute intermittent porphyria and the A and B loci of the HLA system. Tissue Antigens 13:273–277, 1979
Wetterberg L: Report on an international survey of safe and unsafe drugs in acute intermittent porphyria.In Supplement to the Proceedings of the I. International Porphyrin Meeting on Porphyrins in Human Diseases M Doss, P Nawrocki (eds). Freiburg im Breisgau, 1976, p 191
Perlroth MG, Tschudy DP, Ratner A, Spaur W, Redeker A: The effect of diet in variegate (South African genetic) porphyria. Metabolism 17:571–581, 1968
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mustajoki, P., Vuoristo, M. & Reunala, T. Celiac disease or dermatitis herpetiformis in three patients with porphyria. Digest Dis Sci 26, 618–621 (1981). https://doi.org/10.1007/BF01367674
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01367674