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Laser microprobe mass analysis for the identification of asbestos fibers in lung tissue and broncho-alveolar washing fluid

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Abstract

Laser microprobe mass analysis (LAMMA) provides qualitative information on mineral fibers in human lung tissue, ashed lung samples and bronchoalveolar lavage fluid (BAL). Chemical surface alternations caused by fluids in the human lung can be characterized. In laser desorption conditions the negative spectra indicate the presence of ferritin. The measurements support and complement data obtained by electron microscopy.

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References

  1. M. R. Becklake,Clin. and Invest. Medicine 1983,6, 305.

    Google Scholar 

  2. B. Gylseth, A. Churg, J. M. Davis, N. Johnson, A. Morgan, G. Move, A. Rogers, V. L. Roggli,Scand. J. Work, Environm. and Health 1986,11 (2), 107.

    Google Scholar 

  3. V. L. Roggli, P. Ingram, R. W. Linton, W. F. Gutknecht, P. Mastin, J. D. Shellburne,Environm. Health Persp. 1984,56, 163.

    Google Scholar 

  4. D. G. Taylor, P. A. Baron, S. A. Shulman, G. W. Carter,Amer. Ind. Hygiene Assoc. J. 1984,45 (2), 84.

    Google Scholar 

  5. M. A. Spycher, J. R. Ruttner,Staub-Reinhaltung der Luft 1985,45 (1), 12.

    Google Scholar 

  6. A. J. Rogers,Ann. Occup. Hygiene 1984,28 (1), 1.

    Google Scholar 

  7. V. L. Roggly, P. C. Pratt, A. R. Brady,Brit. J. Ind. Medicine 1986,43, 18.

    Google Scholar 

  8. E. Denoyer, R. E. Van Grieken, F. C. Adams, D. F. Natusch,Anal. Chem. 1982,54, 26A.

    Google Scholar 

  9. E. Michiels, L. Van Vaeck, R. Gijbels,Scanning Electron Microscopy 1984,III, 1111.

    Google Scholar 

  10. A. H. Verbueken, F. J. Bruynseels, R. E. Van Grieken,Biomed. Mass Spectrom. 1985,12, 438.

    Google Scholar 

  11. J. K. De Waele, F. C. Adams,Scanning Electron Microscopy 1985,III, 935.

    Google Scholar 

  12. T. Ehrenreich, A. D. Mackler, A. Langer, I. J. Selikoff,Ann. Clin. Lab. Sci. 1973,3, 118.

    Google Scholar 

  13. M. G. Williams, R. F. Dodson, C. Corn, G. A. Hurst,J. Toxicol. Environm. Health 1982,10, 627.

    Google Scholar 

  14. M. Neuberger, M. Grasserbauer, H. W. Müller, B. Schwaighofer,17. Tagung d. Österr. Gesellschaft für Lungenerkrankungen, 1983, p. 49.

  15. J. Bignon, M.-C. Jaurand, P. Sebastien, in:The Lung in Its Environment (G. Bonsignore, J. Cummings, eds.), Plenum, New York, 1982, p. 159.

    Google Scholar 

  16. A. S. Rebuck, A. C. Brande,Arch. Intern. Medicine 1983,143, 950.

    Google Scholar 

  17. P. De Vuyst, J. Jedwab, P. Dumortier, G. Vandernoten, R. Vandeweyer, J. C. Yernault,Amer. Rev. Respir. Dis. 1982,126, 972.

    Google Scholar 

  18. J. T. Stasny, C. Husack, F. R. Allright, D. V. Schumacker, D. S. Sweigert, K. Boyer,Scanning Electron Microscopy 1979,I, 587.

    Google Scholar 

  19. M. Grasserbauer, M. Neuberger, H. W. Müller, B. Schwaighofer,Fresenius' Z. Anal. Chem. 1984,317, 293.

    Google Scholar 

  20. J. K. De Waele, F. C. Adams, in:Physical and Chemical Characterization of Individual Airborne Particles (K. R. Spurny, ed.), Ellis Horwood, Chichester, 1986, chapt. 16, pp. 271–297.

    Google Scholar 

  21. M. Neuberger, W. Grundorfer, M. Haider, R. Konigshofer, H. W. Müller, A. Raber, B. Riedmüller, B. Schwaighofer,Zbl. Bakt. Hyg., I. Abt. Orig. 1978,B 167, 391.

    Google Scholar 

  22. M. Neuberger, in:Asbestos: Epidemiological Contributions to Risk Evaluation, Facultas, Vienna, 1981.

    Google Scholar 

  23. M. Neuberger, P. Ambrosch,Wien. Klin. Wochenschr. 1985,97, 289.

    Google Scholar 

  24. M. Neuberger, M. Kundi, H. P. Friedl,Arch. Env. Health 1984,39, 261.

    Google Scholar 

  25. T. Burilkov,4th Intern. Pneumoconiosis Conf. Proceedings, Vol. 280, Bukarest, Romania, 1971.

    Google Scholar 

  26. R. Kiviluoto,Ann. New York Acad. Sci. 1965, 132.

  27. T. Burilkov,Wissenschaft und Umwelt 1985,2, 146.

    Google Scholar 

  28. K. Kolev,Internat. Symposium Staubbekämpfung und Staublungenerkrankungen, Sliven, Bulgarien, 1986.

    Google Scholar 

  29. M. Haider, M. Neuberger,Beiträge des Bundesministeriums f. Gesundheit u. Umweltschutz 1981,2, 1–66.

    Google Scholar 

  30. A. M. Langer, I. B. Rubin, I. J. Selikoff,J. Histochem. Cytochem. 1972,20, 723.

    Google Scholar 

  31. R. Derricott, in:Asbestos, Vol. 1: Properties, Applications and Hazards (L. Michaels and S. S. Chissick, eds.), Wiley, Chichester, 1979, p. 305.

    Google Scholar 

  32. V. Timbrell, R. E. Rendall,Powder Technology 1971/1972,5, 279.

    Google Scholar 

  33. J. K. De Waele, P. Van Espen, E. F. Vansant, F. C. Adams,Proc. 17th Annual Conf. Microbeam Analysis, Washington D. C., August 1982 (K. F. Heinrich, ed.), San Francisco Press, San Francisco, 1982, p. 371.

    Google Scholar 

  34. R. G. Crystal, J. E. Gadek, V. J. Ferrans,Amer. J. Med. 1981,70, 542.

    Google Scholar 

  35. M. Blount, P. F. Holt, A. A. Leach,Biocbem. J. 1966,101, 204.

    Google Scholar 

  36. S. R. Botham, P. F. Holt,Kongreßbericht der V. Internationalen Staublungentagung, Münster, 1967.

  37. L. J. Cralley, R. G. Reenan, J. R. Lynch, W. S. Lainhart,Amer. Ind. Hyg. Assoc. J. 1968,29, 129.

    Google Scholar 

  38. P. Gross, L. J. Cralley, R. T. De Treville,Amer. Ind. Hyg. Assoc. J. 1967,28, 541.

    Google Scholar 

  39. F. D. Pooley, P. D. Oldham, Un Chang-Myn, J. C. Wagner,Pneumoconiosis Int. Conf. (H. A. Shapiro, ed.), Oxford Univ. Press, Cape Town, 1969, p. 108.

    Google Scholar 

  40. P. M. Harrison, T. G. Hoy,Inorganic Biochemistry, Vol. 1 (G. L. Eichhorn, ed.), Elsevier, Amsterdam, 1973, p. 253.

    Google Scholar 

  41. F. Valerio, M. Veggi, L. Santi,Environm. Res. 1980,21, 186.

    Google Scholar 

  42. O. H. Lowry, N. J. Roselrough, A. L. Farr, R. J. Randall,J. Biol. Chem. 1951,193, 265.

    Google Scholar 

  43. F. L. Pundsack,J. Phys. Chem. 1955,59, 892.

    Google Scholar 

  44. J. A. Verlinden, J. K. De Waele, I. M. Swenters, F. C. Adams,Surface and Interface Analysis 1984,6, 286.

    Google Scholar 

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Authors and Affiliations

  1. Department of Chemistry, Micro and Trace Analysis Center (MITAC), University of Antwerp (UIA), B-2610, Wilrijk, Belgium

    J. K. De Waele & F. C. Adams

  2. Department of Pneumology, Antwerp University Hospital (U.Z.A.), B-2520, Edegem, Belgium

    P. A. Vermeire

  3. Institute of Environmental Hygiene, University of Vienna, A-1090, Vienna, Austria

    M. Neuberger

Authors
  1. J. K. De Waele
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  2. F. C. Adams
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  3. P. A. Vermeire
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  4. M. Neuberger
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De Waele, J.K., Adams, F.C., Vermeire, P.A. et al. Laser microprobe mass analysis for the identification of asbestos fibers in lung tissue and broncho-alveolar washing fluid. Mikrochim Acta 90, 197–213 (1986). https://doi.org/10.1007/BF01364301

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  • DOI: https://doi.org/10.1007/BF01364301

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