Summary
Monolayer cultures of the fibroblast-like Chinese hamster cell-line 19/1 were irradiated in the G2-phase of the cell cycle byπ −-mesons (6 rad/min peak-pion dose rate). Frequencies of induced single- and isochromatid breaks, acentric fragments and interchanges were compared with data obtained from 140 kV X-rays.
The RBE-values were for the pion dose peak between 0.8–1.2 and for the pion dose plateau 0.5–0.9. Whereas for single chromatid breaks there was no significant difference between X-rays and peak pions for identical physical doses, the isochromatid breaks alone showed a significantly higher frequency for 100 rad peak pions.
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Mindek, G., Blattmann, H., Cordt, I. et al. Chromatid breaks induced in Chinese hamster cells by low doses (12–100 rad) ofπ −-mesons. Radiat Environ Biophys 16, 279–282 (1979). https://doi.org/10.1007/BF01358290
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DOI: https://doi.org/10.1007/BF01358290