Skip to main content
Log in

Concomitant natural infection with L. donovani and L. major: A case report from Iraq

Simultane Infektion mit L. donovani und L. major: Eine Fallstudie im Irak

Infection simultanée par L. donovani et L. major: Une étude rapporte en Iraq

  • Published:
Sozial- und Präventivmedizin

Summary

This is a case report of kala-azar with cutaneous leishmaniasis. Upon admission, the patient had fever, hepatosplenomegaly and an ulcer on her cheek. The patient responded to Pentostam. Isoenzyme studies of parasite isolates from the the bone marrow and from the cutaneous lesion revealed that these were L. donovani and L. major, respectively. This is the first report in Iraq of a proven concomitant infection with two species of leishmania parasites.

Zusammenfassung

Wir präsentieren eine Fallstudie von Kala-Azar mit gleichzeitiger kutaner Leishmaniose, Die Patientin hatte Fieber, Hepatosplenomegalie und einen Ulcus an der einen Wange. Sie sprach auf Pentostam an. Die Analyse der Isoenzym-Profile der Parasiten aus einer Knochenmarks-Punktion sowie aus dem Ulcus wiesen nach, dass es sich dabei um L. donovani und um L. major handelte. Diese Studie ist die erste Beschreibung einer simultanen Infektion mit L. donovani und mit L. major im Irak.

Résumé

Notre étude rapporte un cas de Kala-Azar accompagné d'une leishmaniose cutanée. La patiente avait la fièvre, une hépatosplénomégalie et un ulcère à une de ses joux. L'infection répondait bien à la Pentostame. L'analyse des isoenzymes montrait que les parasites isolés de la moile osseuse représentaient L. donovani, pendant que ceux de la lésion cutanée représentaient L. major. Notre rapport constitue la première documentation d'un cas d'une infection simultanée par L. donovani et L. major en Iraq.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Al-Hussayni NK, Rassam MB, Jawdat SZ, Wahid FN. Numerical taxonomy of some Old World Leishmania species. Trans R Soc Trop Med Hyg 1987;81:581–586.

    Google Scholar 

  2. Al-Jeboori TI, Evans DA. Leismania spp. in Iraq. Electrophoretic isoenzyme patterns. I. Visceral leishmaniasis. Trans R Soc Trop Med Hyg 1980a;72:169–177.

    Google Scholar 

  3. Al-Jeboori TI, Evans DA. Leishmania spp in Iraq. Electrophoretic isoenzyme patterns. II. Cutaneous leishmaniasis. Trans R Soc Trop Med Hyg 1980b;74:178–184.

    Google Scholar 

  4. Rassam MB, Al-Mudaffar SA, Chance ML. Isoenzyme characterization of Leishmania species from Iraq. Ann Trop Med Parasit 1979;73:527–534.

    Google Scholar 

  5. Sukkar FJ. Kala Azar in Iraq 1975. Bull End Dis 1979;XIX:29–38.

    Google Scholar 

  6. Rassam MB, Jawdat SZ, Al-Hussayni NK, Rifaat LK, Sukkar FJ. Biochemical study on Leishmania with some epidemiological application on leishmaniasis in Iraq. J Biol Sci Baghdad 1985;16:83–103.

    Google Scholar 

  7. Morsy TA, Sarwat MA, Al-Shaiby AZ, Fawzy AF, Arafa MA. Isoenzyme characterization of Leishmania isolates from patients in El-Nour Specialized Hospital. J Egypt Soc Parasitol 1993;23:871–876.

    Google Scholar 

  8. Killick-Kendrick R, Peters W. Leishmaniasis in Arabia. An annotated bibliography. Am J Trop Med Hyg 1991;44:1–64.

    Google Scholar 

  9. Dereure J, Rioux JA, Khiami A, Pratlong F, Perieries J, Martini A. Ecoépidemiologie des leishmanioses en Syrie. 2. Présence, chez le chien, de Leishmania infantum et Leishmania tropica. Ann Parasitol Hum Comp 1991;66:252–255.

    Google Scholar 

  10. Peters W. Heterogeneity of cutaneous leishmaniasis with emphasis on the Old World. Schweiz Med Wochenschr 1993;123:1237–1249.

    Google Scholar 

  11. Alvar J, Ballesteros JA, Soler R, Benito A, Vaneys GJJM, Schoone GJ, Cabrer B. Mucocutaneous leishmaniasis due to Leishmania infantum — biochemical characterization. Am J Trop Med Hyg 1990;43:614–618.

    Google Scholar 

  12. Rioux JA, Lanotte G. Leishmania infantum as a cause of cutaneous leishmaniasis. Trans R Soc Trop Med Hyg 1990;84:898.

    Google Scholar 

  13. Mebrahtu Y, Lawyer P, Githure J, Were JB, Muigal R, Hendricks L, Leeuwenburg J, Koech D, Roberts C. Visceral leishmaniasis unresponsive to pentostam caused by Leishmania tropica in Kenya. Am J Trop Med Hyg 1989;41:289–294.

    Google Scholar 

  14. Yebra M, Segovia J, Manzano L, Vargas JA, Bernaldo de Quiros L, Alvar J. Disseminated-to-skin Kala-azar and the acquired immunodeficiency syndrome. Ann Intern Med 1988;108:490–491.

    Google Scholar 

  15. Coutinho SG, Nunes MP, Marzochi MC, Tramontano N. A survey of American cutaneous and visceral leishmaniasis among 1342 dogs from areas in Rio de Janeiro where the human diseases occur. Mem Inst Oswaldo Cruz 1985;80:17–22.

    Google Scholar 

  16. Ashford RW, Smith DH. Leishmaniasis in the Sudan, Ethiopia and Kenya. In: Chang K. P., Bray R. S. eds. Human Parasitic Diseases, vol 1. Amsterdam: Elsevier, 1985:337–391.

    Google Scholar 

  17. Evans DA, Lanham SM, Baldwin CI, Peters W. The isolation and isoenzyme characterization of Leishmania brazilienses subsp. from patients with cutaneous leishmaniasis acquired in Belize. Trans R Soc Trop Med Hyg 1984;78:35–42.

    Google Scholar 

  18. Urjel R, Recacoechea M, LaFuente C, Orellana H. A simple method for the collection of material from cutaneous and mucocutaneous leishmaniasis lesions. Trans R Soc Trop Med 1983;77:882–883.

    Google Scholar 

  19. Jawad J, Khairy N, Sukkar F. Evaluation of an indirect immunofluorescence antibody test for the diagnosis of Kala Azar in Iraq. J Fac Med Baghdad 1981;23:189–196.

    Google Scholar 

  20. Al-Awkati N, Khairy N. Post-Kala Azar dermal leishmanoid in an Iraqi child. J Fac Med Baghdad 1980;22:305–309.

    Google Scholar 

  21. Jawdat SZ, Ali NA, Rifaat LK, Rutha KY. The incidence of Kala-Azar in an endemic focus in central Iraq. J Biol Sci Baghdad 1983;14:81–87.

    Google Scholar 

  22. Sukkar F. Some statistical data on Kala Azar in Iraq. Bull End Dis 1976;XVII:75–79.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Al-Diwany, L.J., Al-Awkati, N.A., Atia, M. et al. Concomitant natural infection with L. donovani and L. major: A case report from Iraq. Soz Präventivmed 40, 234–238 (1995). https://doi.org/10.1007/BF01354478

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01354478

Keywords

Navigation