Journal of Comparative Physiology A

, Volume 158, Issue 2, pp 195–202

Deoxyglucose mapping of nervous activity induced inDrosophila brain by visual movement

III. Outer rhabdomeres absentJK84, small optic lobesKS58 and no object fixation EB12, visual mutants
  • Isabelle Bülthoff
Article

DOI: 10.1007/BF01338562

Cite this article as:
Bülthoff, I. J. Comp. Physiol. (1986) 158: 195. doi:10.1007/BF01338562

Summary

Autoradiographs of the brains of the visual mutantsouter rhabdomeres absentJK84 (ora),small optic lobesKS58 (KS58) andno object fixation EB12 (B12) have been obtained by the deoxyglucose method. The patterns of metabolic activity in the optic lobes of the visually stimulated mutants is compared with that of similarly stimulated wildtype (WT) flies which was described in Part I of this work (Buchner et al. 1984b).

In the mutantKS58 the optomotor following response to movement is nearly normal despite a 40–45% reduction of volume in the visual neuropils, medulla and lobula complex. InB12 flies the volume of these neuropils and the optomotor response are reduced. In autoradiographs of both mutants the pattern of neuronal activity induced by stimulation with moving gratings does not differ substantially from that in the WT. It suggests that only neurons irrelevant to movement detection are affected by the mutation. However, in the lobula plate of someKS58 flies and in the second chiasma of allB12 flies, the pattern of metabolic activity differs from that observed in WT flies. Up to now no causal relation has been found between the modifications described in behaviour or anatomy and those observed in the labelling of these mutants.

In the ommatidia ofora flies the outer rhabdomeres are lacking while the central photoreceptors appear to be normal. Stimulus-specific labelling is absent in the visual neuropil of these mutants stimulated with movement or flicker. This result underlines the importance of the outer rhabdomeres for visual tasks, especially for movement detection.

Abbreviations

DG

deoxyglucose

KS58

small optic lobesKS58

B12

no object fixation EB12

JK84

ora outer rhabdomeres absentJK84

WT

wildtype

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • Isabelle Bülthoff
    • 1
  1. 1.Max-Planck-Institut für biologische KybernetikTübingenFederal Republic of Germany
  2. 2.Center for Biological Information ProcessingMassachusetts Institute of Technology, E25-201CambridgeUSA

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