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Radiation and Environmental Biophysics

, Volume 16, Issue 1, pp 43–48 | Cite as

Contrasting oxygen-effects in the inactivation of ribonuclease A by N 3 , (SCN) 2 andOH radicals

  • Walter A. Prütz
Article

Summary

N 3 exhibits higher efficiency thanOH in the inactivation of RNase in de-acerated (neutral) aqueous solution. In O2-saturated solution theOH-induced inactivation is enhanced, but N 3 and (SCN) 2 become remarkably inefficient. Our results suggest that semi-oxidized tyrosine, the predominant initial defect induced by N 3 and (SCN) 2 but not byOH, can be re-reduced upon reaction with O 2 or cysteine.

Keywords

Aqueous Solution Tyrosine Cysteine Environmental Physic Initial Defect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Walter A. Prütz
    • 1
  1. 1.Institut für Biophysik und StrahlenbiologieUniversität FreiburgFreiburgFederal Republic of Germany

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