Abstract
Continuous peritoneal dialysis significantly prolonged mean length of survival and reduced lethality rate of taurocholate-induced pancreatitis in the rat. The effect was improved by compensating protein loss due to pancreatitis and dialysis treatment. The beneficial effect of intravenous albumin treatment was enhanced when combined with dialysis treatment. Using hypothermic dialysate or adding aprotinin intraperitoneally had no additional effect.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ceutzfeldt W, Scheler F, Quellhorst E, Schmidt H: Akutes Nierenversagen bei Pankreatitis. Arch Klin Med 213:197–218, 1967
Bolooki H, Gliedman ML: Peritoneal dialysis in the tratment of acute pancreatitis. Surgery 64:466–471, 1968
Geokas MC, Olsen H, Barbour B, Rinderknecht H: Peritoneal lavage in the treatment of acute hemorrhagic pancreatitis. Gastroenterology 58:950, 1970
Gjessing J, Hagberg AL, Hornacek L, Moberg B, Mörtberg A, Nylander B, Oskarsson BM, Ruthström E, Tomlin P, Öquist L: Other use of peritoneal dialysis in the intensive care unit. Opusc Med 19:53–55, 1974
Heissmeyer H, Heinze V, Heni N, Herkel L, Hoppe-Seyler G, Jontofsohn R, Nolte J, Schollmeyer P: Therapie der akuten Pankreatitis mit der Langzeitperitonealdialyse. Verh Dtsch Ges Inn Med 81:709–712, 1975
Nemeth E, Fodor I, Folly G, Horvath EJ, Papp M: La dialyse péritonéale dans le traitment de la pancréatite aiguë expérimentale hémorrhagique. Lyon Chir 68:433–435, 1972
Rodgers RE, Carey LC: Peritoneal lavage in experimental pancreatitis in dogs. Am J Surg 111:792–794, 1966
Rosato EF, Chu WH, Mullen JL, Rosato FE: Peritoneal lavage treatment of experimental pancreatitis. J Surg Res 12:138–140, 1972
Rosato EF, Mullis WF, Rosato FE: Peritoneal lavage therapy in hemorrhagic pancreatitis. Surgery 74:106–115, 1973
Lankisch PG, Koop H, Winckler K, Quellhorst E, Schmidt H: Experimental model for peritoneal dialysis in small laboratory animals. Clin Nephrol 4:251–252, 1975
Lankisch PG, Winckler K, Bokermann M, Schmidt H, Creutzfeldt W: The influence of glucagon on acute experimental pancreatitis in the rat. Scand J Gastroenterol 9:725–729, 1974
Weichselbaum TE: An accurate and rapid method for the determination of proteins in small amounts of blood serum and plasma. Am J Clin Pathol 10:40–49, 1946
Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the folin phenol reagent. J Biol Chem 193:265–275, 1951
McGovern JJ, Jones AR, Steinberg AG: The hematocrit of capillary blood. N Engl J Med 253:308–312, 1955
Lankisch PG, Koop H, Winckler K, Quellhorst E, Schmidt H: Peritoneal dialysis in small laboratory animals. Experientia 33:743–744, 1977
Rasmussen BL: Hypothermic peritoneal dialysis in the treatment of acute experimental hemorrhagic pancreatitis. Am J Surg 114:716–721, 1967
Ohlsson K, Tegner H: Experimental pancreatitis in the dog. Demonstration of trypsin in ascites fluid, lymph and plasma. Scand J Gastroenterol 8:129–133, 1973
Elliot DW, Zollinger RM, Moore R, Ellison EH: The use of human serum albumin in the management of acute pancreatitis. Gastroenterology 28:563–587, 1955
Author information
Authors and Affiliations
Additional information
Supported by Deutsche Forschungsgemeinschaft, Bad Godesberg LA 369/1.
Rights and permissions
About this article
Cite this article
Lankisch, P.G., Koop, H., Winckler, K. et al. Continuous peritoneal dialysis as treatment of acute experimental pancreatitis in the rat. Digest Dis Sci 24, 111–116 (1979). https://doi.org/10.1007/BF01324737
Issue Date:
DOI: https://doi.org/10.1007/BF01324737