Skip to main content
Log in

Applications of the selective periodate oxidation of sialic acids III. Identification of neuraminidase-sensitive and neuraminidase-resistant sialic acids and their side chain O-acyl variants

  • Short Communication
  • Published:
The Histochemical Journal Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Barger, I. D. &Delamater, E. D. (1948) The use of thionyl chloride in the preparation of Schiff reagent.Science 108, 121–2.

    Google Scholar 

  • Cheresh, D. A. &Reisfeld, R. A. (1984) O-acylation of disialoganglioside GD3 by human melanoma cells creates a unique antigenic determinant.Science 225, 355–6.

    Google Scholar 

  • Culling, C. F. A. (1974)Handbook of Histochemical Histopathological Technique, 3rd edn. London: Butterworth.

    Google Scholar 

  • Diaz, S. &Varki, A. (1985) Metabolic labelling of sialic acids in tissue culture cell lines: methods to identify substituted and modified radioactive neuraminic acids.Anal. Biochem. 150, 32–46.

    Google Scholar 

  • Drzenick, R. (1973) Substrate specificity of neuraminidases.Histochem. J. 5, 271–90.

    Google Scholar 

  • Gottschalk, A. &Drzenick, R. (1972)Glycoproteins, their Composition Structure and Function, BBA library 5A (edited byGottschalk, A.), pp. 381–402. Amsterdam: Elsevier.

    Google Scholar 

  • Haverkamp, J., Schauer, R., Wember, M., Kamberling, J. P. &Vliegenthart, J. F. P. (1975) Synthesis of 9-O-acetyl and 4, 9-di-O-acetyl neuraminic acid methyl glycoside.Z. Physiol. Chem. 356, 1575–83.

    Google Scholar 

  • Lillie, R. D. &Pizzolato, P. (1972) Histochemical use of borohydrides as aldehyde blocking reagents.Stain Technol. 43, 13–16.

    Google Scholar 

  • Poon, H. R., Reid, P. E., Ramey, C. W., Dunn, W. L. &Clay, M. G. (1983) Removal of O-acetylated sialic acids from rat colonic epithelial glycoproteins by cell free extracts of rat faeces.Can. J. Biochem. Cell Biol. 61, 868–74.

    Google Scholar 

  • Reid, P. E., Culling, C. F. A., Ramey, C. W., Dunn, W. L. &Clay, M. G. (1977) A simple method for the determination of the O-acyl substitution pattern of the sialic acids of colonic epithelial glycoprotein.Can. J. Biochem. 55, 493–503.

    Google Scholar 

  • Reid, P. E., Culling, C. F. A., Dunn, W. L., Ramey, C. W. &Clay, M. G. (1984) Chemical and histochemical studies of normal and diseased human gastrointestinal tract I. A comparison between histologically normal colon, colonic tumours, ulterative colitis and diverticular disease of the colon.Histochem. J. 16, 235–51.

    Google Scholar 

  • Reid, P. E., Owen, D. A., Dunn, W. L., Ramey, C. W., Lazosky, D. A. &Clay, M. G. (1985) Chemical and histochemical studies of normal and diseased gastrointestinal tract III. Changes in the histochemical and chemical properties of the epithelial glycoproteins in the mucosa close to colonic tumours.Histochem. J. 17, 171–81.

    Google Scholar 

  • Reid, P. E., Volz, D., Park, C. M., Owen, D. A. &Dunn, W. L. (1987) Methods for the identification of side chain O-acyl substituted sialic acids and for the simultaneous visualization of sialic acid, its side chain O-acyl variants and O-sulphate ester.Histochem. J. 19, 396–8.

    Google Scholar 

  • Schauer, R. (1982) Chemistry., metabolism and biological functions of sialic acid.Adv. Carb. Chem. Biochem. 40, 131–234.

    Google Scholar 

  • Schauer, R. &Faillard, H. (1968) The action specificity of neuraminidase: the action of bacterial neuraminidase on isomeric N, O-diacetyl neuraminic acid glycoside in the submaxillary mucin of horse and cow.Z. Physiol. Chem. 349, 961–8.

    Google Scholar 

  • Shukla, A. K. &Schauer, R. (1982) Fluorometric determination of unsubstituted and 9(8)-O-acylated sialic acids in erythrocyte membrane.Z. Physiol. Chem. 363, 255–62.

    Google Scholar 

  • Sugihara, K. &Jass, J. R. (1986) Colorectal goblet cell sialomucin heterogeneity in relation to malignant disease.J. Clin. Pathol. 39, 1088–95.

    Google Scholar 

  • Varki, A. &Diaz, S. (1983) A neuraminidase fromStreptococcuss sanguis that can release O-acetylated sialic acids.J Biol. Chem. 258, 12465–71.

    Google Scholar 

  • Varki, A. &Diaz, S. (1984) The release and purification of sialic acids from glycoconjugates: methods to minimize the loss and migration of O-acetyl groups.Anal. Biochem. 137, 236–47.

    Google Scholar 

  • Volz, D., Reid, P. E., Park, C. M., Owen, D. A. &Dunn, W. G. (1987a) A new method for the selective periodate oxidation of total tissue sialic acids.Histochem. J. 19, 311–8.

    Google Scholar 

  • Volz, D., Reid, P. E., Park, C. M., Owen, D. A. &Dunn, W. G. (1987b) Histochemical procedures for the simultaneous visualization of neutral sugars and either sialic acid and its side chain O-acyl variants or O-sulphate ester I. Methods based upon the selective periodate oxidation of sialic acids.Histochem. J. 19, 249–56.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Reid, P.E., Arratoon, C. & Owen, D.A. Applications of the selective periodate oxidation of sialic acids III. Identification of neuraminidase-sensitive and neuraminidase-resistant sialic acids and their side chain O-acyl variants. Histochem J 20, 645–650 (1988). https://doi.org/10.1007/BF01324085

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01324085

Keywords

Navigation