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Quantitative analysis of the chromosome damage at first division of human lymphocytes after60COγ-Irradiation

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References

  1. Apelt F, Kolin-Gerresheim I, Bauchinger M (1981) Azathioprine, a clastogen in human somatic cells? Analysis of chromosome damage and SCE in lymphocytes after exposure in vivo. Mutat Res 88: 61–72

    Google Scholar 

  2. Bauchinger M (1983) Cytogenetic effects in human lymphocytes as a dosimetry system. In: Eisert WG, Mendelsohn ML (eds) Proceedings of “Biological dosimetry: cytometric approaches to mammalian systems”. Neuherberg, 14–16 October 1982. Springer, Berlin Heidelberg New York (in press)

    Google Scholar 

  3. Bauchinger M, Schmid E (1973) Chromosome aberrations in human lymphocytes after X-irradiation in vitro, II. Analysis of primary processes in the formation of dicentric chromosomes. Mutat Res 20: 107–113

    Google Scholar 

  4. Bauchinger M, Schmid E, Rimpl G (1974) Interaction distance of primary lesions in the formation of dicentric chromosomes after irradiation of human lymphocytes with 3 MeV electrons in vitro. Mutat Res 25: 83–87

    Google Scholar 

  5. Bauchinger M, Schmid E, Dresp J (1979) Calculation of the dose-rate dependence of the dicentric yield after Coγ-irradiation of human lymphocytes. Int J Radiat Biol 35: 229–233

    Google Scholar 

  6. Bauchinger M, Kühn H, Dresp J, Schmid E, Streng S (1983) Dose-effect relationship for 14.5 MeV (d+T) neutron-induced chromosome aberrations in human lymphocytes irradiated in a man phantom. Int J Radiat Biol 43: 571–578

    Google Scholar 

  7. Bender MA (1969) Human radiation cytogenetics. In: Augstein MG, Mason R, Zelle M (eds) Advances in radiation biology, Vol 3. Academic Press, New York, pp 215–275

    Google Scholar 

  8. Crossen PE, Morgan WF (1977) Analysis of human lymphocyte cell cycle time in culture measured by sister chromatid differential staining. Exp Cell Res 104: 453–457

    Google Scholar 

  9. Doggett MA, Mc Kenzie H (1983) An analysis of the distribution and dose response of chromosome aberrations in human lymphocytes after in vitro exposure to137Cesium gamma radiation. Radiat Environ Biophys 22: 33–51

    Google Scholar 

  10. Dolphin GW (1978) A review of in vitro dose-effect relationships. In: Evans HJ, Lloyd DC Mutagen induced chromosome damage in man. University Press, Edinburgh, pp 1–8

    Google Scholar 

  11. Edwards AA, Lloyd DC, Purrott RJ (1979) Radiation induced chromosome aberrations and the Poisson distribution. Radiat Environ Biophys 16: 89–100

    Google Scholar 

  12. Kellerer AM, Brenot J (1974) On the statistical evaluation of dose-response function. Radiat Environ Biophys 11: 1–13

    Google Scholar 

  13. Kolin-Gerresheim I, Bauchinger M (1981) Dependence of the frequency of harlequin-stained cells on BrdU concentration in human lymphocyte cultures. Mutat Res 91: 251–254

    Google Scholar 

  14. Lloyd DC (1983) Overview of biological dosimetry of chromosomes and its application using conventional methods. In: Eisert WG, Mendelsohn ML (eds) Proceedings of “Biological dosimetry: cytometric approaches to mammalian systems” Neuherberg, 14–16 October 1982. Springer, Berlin Heidelberg New York (in press)

    Google Scholar 

  15. Radhakrishna Rao C, Chakravarti J (1956) Some small sample tests of significance for a poisson distribution. Biometrics 12: 264–282

    Google Scholar 

  16. Savage JRK (1970) Sites of radiation induced chromosome exchanges. Curr Top Radiat Res 6: 129–194

    Google Scholar 

  17. Schmid E, Bauchinger M, Mergenthaler W (1976) Analysis of the time relationship for the interaction of X-ray-induced primary breaks in the formation of dicentric chromosomes. Int J Radiat Biol 30: 339–346

    Google Scholar 

  18. Schmid E, Bauchinger M (1980) Analysis of primary processes in the formation of acentric fragments. Radiat Environ Biophys 17: 143–149

    Google Scholar 

  19. Scott D, Lyons CY (1979) Homogenous sensitivity of human peripheral blood lymphocytes to radiation-induced chromosome damage. Nature (London) 278: 756–758

    Google Scholar 

  20. Streng S, Bauchinger M (1983) Weighted identity test for the comparison of dose-response functions of radiation-induced chromosome aberrations. Radiat Environ Biophys 22: (in press)

  21. Virsik RP, Harder D (1981) Analysis of radiation-induced acentric fragments in human G0 lymphocytes. Radiat Environ Biophys 19: 29–40

    Google Scholar 

  22. Virsik RP, Harder D, Hausmann I (1977) The RBE of 30 kV X-rays for the induction of dicentric chromosomes in human lymphocytes. Radiat Environ Biophys 14: 109–121

    Google Scholar 

  23. Wagner R, Schmid E, Bauchinger M (1983) Application of conventional and FPG staining for the analysis of chromosome aberrations induced by low levels of dose in human lymphocytes. Mutat Res 109: 65–71

    Google Scholar 

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Bauchinger, M., Schmid, E., Streng, S. et al. Quantitative analysis of the chromosome damage at first division of human lymphocytes after60COγ-Irradiation. Radiat Environ Biophys 22, 225–229 (1983). https://doi.org/10.1007/BF01323712

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  • DOI: https://doi.org/10.1007/BF01323712

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