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A study of cell survival in mammalian cells exposed to spatially correlated triads of protons

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Summary

Cellular survival results for late-S Chinese hamster V79 cells exposed to triads of protons of variable mean separations are reported. The data are analyzed within the framework of the Theory of Dual Radiation Action [8]. This analysis provides a new estimation of the function γ(x) representing the probability of two energy transfers separated by the distancex to produce a lesion. In agreement with an earlier study [6] involving pairs of deuterons, it is concluded that:a) the process of lesion formation depends strongly on the relative separation of energy deposition events, andb) intratrack and intertrack lesions correspond to substantially different separations of pairwise energy transfers.

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Zaider, M., Bird, R.P., Rossi, H.H. et al. A study of cell survival in mammalian cells exposed to spatially correlated triads of protons. Radiat Environ Biophys 22, 239–249 (1983). https://doi.org/10.1007/BF01323675

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