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Regional blood flow in rats exposed to supralethal doses of whole body X-irradiation

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Summary

Relative blood flow in different organs of the supralethally (3 kR) whole body X-irradiated rat was studied using labeled 15 µ microspheres. Immediately after irradiation blood flow in brain diminishes. From 10 to 20 hrs a phase of increase in blood flowing to many parenchymal organs ensues. A second maximum 45 to 50 hrs and a third one at 60 hrs. In most organs except in brain and liver relative blood flow diminishes before death. The genesis of these changes as signs of a slowly developing shock is discussed.

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Supported by the Schutzkommission, Publication No. 1050 of the Euratom Biology Division.

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Watters, C., Gerber, G.B. Regional blood flow in rats exposed to supralethal doses of whole body X-irradiation. Radiat Environ Biophys 12, 303–313 (1975). https://doi.org/10.1007/BF01323418

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  • DOI: https://doi.org/10.1007/BF01323418

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