Summary
Human adenoviruses (Ad) 5 and 7 multiplied poorly in guinea-pig cell cultures as compared to HeLa cells. Ad 7 had a modified polypeptide composition with a major 43 K component. This change persisted for up to 4 passages in HeLa cells. Ad 5 was not changed by passage in guinea-pig cells.
References
Bhatti, A. R., Weber, J.: Protease of adenovirus type 2: partial characterization. Virology96, 478–485 (1979).
Chardonnet, Y., Lyon, M., Soula, A.: Identification of the adenovirus components during the penetration in HeLa cells by immunofluorescence technique. Arch. Virol.54, 189–199 (1977).
Chou, S. M., Roos, R., Burrell, R., Gutmann, L., Harley, J. B.: Subacute focal adenovirus encephalitis. J. Neuropathol. Exp. Neurol.32, 34–50 (1973).
Faucon, N., Chardonnet, Y., Sohier, R.: Persistence of adenovirus 5 in guineapigs. Infect. Immun.10, 11–15 (1974).
Pereira, H. G., Kelly, B.: Latent infection of rabbits by adenovirus type 5. Nature180, 615–616 (1957).
Reddick, R. A., Lefkowitz, S. S.:In vivo immune responses of rabbits with persistent adenovirus type 5 infection. J. Immunol.103, 687–694 (1969).
Rorke, L. B., Gilden, D. H., Wroblewska, Z., Santoli, D.: Human brain in tissue culture. IV. Morphological characteristics. J. Comp. Neur.161, 329–340 (1975).
Szafarz, D.: An improved method for DNA alkaline gradient analysis and its application to the effect of carcinogens on mouse liver DNA. Biochimie59, 775–778 (1977).
Youngner, J. S.: Monolayer tissue cultures. I. Preparation and standardization of suspension of trypsin dispersed monkey kidney cells. Proc. Soc. exp. Biol. Med.85, 202–205 (1954).
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Thomasset, N., Chardonnet, Y. Properties of human adenoviruses 5 and 7 grown in guinea-pig cells. Archives of Virology 66, 353–358 (1980). https://doi.org/10.1007/BF01320631
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DOI: https://doi.org/10.1007/BF01320631