Summary
The processing of virus polypeptides synthesized in cells infected with HVJ (haemagglutinating virus of Japan—the Sendai strain of parainfluenza 1 virus) was studied. Maturation of a temperature-sensitive(ts) mutant (HVJ-pB) derived from an HVJ carrier culture was inhibited at 38° C incubation. A considerable amount of viral components were made at the restrictive temperature. They were, with the exception of the polypeptide HN, well preserved without a great loss of their function and successfully incorporated into virus particles released after lowering the incubation temperature. The membrane (M) protein seems to be essential for virus morphogenesis.
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Kimura, Y., Örvell, C. & Norrby, E. Assembly of viral structural proteins in cells infected with a temperature-sensitive mutant derived from an HVJ (Sendai virus) carrier culture. Archives of Virology 61, 163–168 (1979). https://doi.org/10.1007/BF01320601
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DOI: https://doi.org/10.1007/BF01320601