Summary
Interferon (IFN) yield after superinduction declined gradually byin vitro senescence of the cells, while it remained unchanged in IFN-pretreated cells. IFN yield after stimulation with Newcastle disease virus remained unchanged byin vitro senescence.
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Komatsu, H., Maehara, N., Shimoda, K. et al. Production of interferon in human diploid cells at different population doubling levels. Archives of Virology 70, 367–371 (1981). https://doi.org/10.1007/BF01320251
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DOI: https://doi.org/10.1007/BF01320251