Summary
The double immuno-diffusion (DID) test has been applied to detect antibody to VIA antigen in sera from various species of African wild ungulates. In conjunction with the serum neutralisation (SN) test it can be used to decide the degree of risk of movement of animals to other countries free from foot and mouth disease (FMD). The value of the test in assessing the history of infection is limited by its relatively low sensitivity and specificity in respect of virus type.
Similar content being viewed by others
References
Cowan, K. M., Graves, J. H.: A third antigenic component associated with foot and mouth disease infection. Virology30, 528–540 (1966).
McVicar, J. W., Sutmoller, P.: Foot and mouth disease: the agar gel diffusion precipitin test for antibody to virus infection associated (VIA) antigen as a tool for epizootiological surveys. Amer. J. Epidemiol.90, 173–278 (1970).
Fernandez, A. A., de Mello, P. A., Gomes, I., Rosenberg, F.: The use of virus infection associated antigen (VIA) in the detection of cattle exposed to foot and mouth disease virus. Biol. Centro Panamer. Fiebre Aftosa, 17–22 (1975).
Rosenberg, F. J., Cruz, H. M., Fernandez, A. A., Martinez, T., Barreto, A.: Prevalence of antibodies against foot and mouth disease virus infection associated antigen (VIA) in cattle of the Paraguay Chaco. Bol. Centr. Panamer. Fiebre Aftosa21, 9–16 (1977).
Grosso, A. M.: La fiebre aftosa en el jardin zoologico de Buenos Aires en los ultimos quince anos. Gac. vet. (B. Aires)20, 69–77.
Macaulay, J. W.: A check list of non-domestic animals reported to have been infected with foot and mouth disease. Bull. epiz. Dis. Afr.12, 127–128 (1964).
Federer, K. E.: Susceptibility of the Agouti (Dasyprocta Aguta) to foot and mouth disease virus. Z.-Bl. Vet. Med.16, 847–854 (1969).
Hedger, R. S., Condy, J. B., Golding, S. M.: Infection of some species of African wildlife with foot and mouth disease virus. J. comp. Pathol.82, 455–461 (1972).
Hedger, R. S.: Foot and mouth disease in wildlife with particular reference to the African buffalo(Syncerus caffer). In:Page, L. A. (ed.), Wildlife Diseases. New York-London: Plenum Press 1976.
Hedger, R. S.: Foot-and-mouth disease and the African Buffalo(Syncerus caffer). J. comp. Pathol.82, 19–28 (1972).
Drager, N.: Immobilisation von afrikanischen Büffeln im Rahmen der Maul- und Klauenseuchebekämpfung in Botswana. Berl. Munch. tierärztl.87, 328–329 (1974).
Hedger, R. S.: The isolation and characterization of foot and mouth disease virus from clinically normal herds of cattle in Botswana. J. Hyg. (Camb.)66, 27 (1968).
Casey, Helen, L.: Standardised complement fixation method and adaptation to microtest. Publ. Hlth. Monogr.74, 1–34 (1965).
Golding, S. M., Hedger, R. S., Talbot, P., Watson, J.: Radial immunodiffusion and serum neutralisation techniques for the assay of antibodies to swine vesicular disease. Res. vet. Sci.20, 142–147 (1976).
Lobo, C. A., Gutierrez, C. A., Marino, O. C. J.: Evaluation d'anticorps induits par infection par le virus de la Fievre Aphteuse. Bull. Off. int. Epiz.81, 287–303 (1974).
Howell, P. G., Young, E., Hedger, R. S.: Foot and mouth disease in the African elephant(Loxodonta Africana) Onderstepoort. J. vet. Res.40, 41–52 (1973).
Author information
Authors and Affiliations
Additional information
visiting Fellow of the “Fundaçaõ de Amparo à Pesquisa do Estado de Saõ Paulo (FAPESP)”
Rights and permissions
About this article
Cite this article
Pinto, A.A., Hedger, R.S. The detection of antibody to virus-infection associated (VIA) antigen in various species of African wildlife following natural and experimental infection with foot and mouth disease virus. Archives of Virology 57, 307–314 (1978). https://doi.org/10.1007/BF01320070
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01320070