Amino Acids

, Volume 14, Issue 4, pp 271–300 | Cite as

A review of physiological and metabolic effects of essential amino acids

  • K. A. Massey
  • C. H. Blakeslee
  • H. S. Pitkow
Review Article


The authors review ten essential amino acids with regard to their metabolic, physiologic and therapeutic effects throughout the human body. Physical properties of these biologically active compounds are discussed as a foundation for their diverse roles in special nitrogen containing products, neurotransmitters, and as alternative energy sources. Both normal and abnormal amino acid metabolism are considered in the areas of digestion, elimination of metabolic products, metabolic intermediates, and defects in these systems. Recent developments in therapeutic applications are further examined for clinical utility and as an economical alternative to traditional clinical treatment modalities.


Essential amino acids Therapeutic applications Physiological effects Metabolism 


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Copyright information

© Springer-Verlag 1998

Authors and Affiliations

  • K. A. Massey
    • 1
  • C. H. Blakeslee
    • 1
  • H. S. Pitkow
    • 1
    • 2
  1. 1.Department of Biomedical SciencesPennsylvania College of Podiatric MedicinePhiladelphiaUSA
  2. 2.Temple University School of Medicine, Department of Physiology, Temple University Health Science CenterTemple University School of Podiatric MedicinePhiladelphiaUSA

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