Summary
Five different isolates of influenza C virus which were isolated over a period of 32 years and from four different continents were compared by RNA genome oligonucleotide fingerprinting analyses. The earliest isolate of influenza C virus was reported in 1949 byTaylor (19) and served as a reference strain for this study.
The results obtained using this technique of comparing relatedness between viruses clearly showed that all strains are distinct. However, the similarities in the pattern of the oligonucleotide fingerprints are marked for the more recent virus isolates (1966–1979), whereas the reference strain C/Taylor shows more pronounced differences.
The results are consistant with the high degree of serological crossreaction amongst influenza C viruses isolated over a long period of time, a property which sets this group of viruses apart from type A and B members of the orthomyxoviridae.
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References
Chakraverty, P.: Antigenic relationship between influenza C viruses. Arch. Virol.58, 341–348 (1978).
Clewley, J., Gentsch, J., Bishop, D. H. L.: Three unique viral RNA species of snowshoe hare and La Crosse bunyaviruses. J. Virol.22, 459–468 (1977).
Compans, R. W., Bishop, D. H. L., Meiter-Ewert, H.: Structural components of influenza C virions. J. Virol.21, 658–665 (1977).
Czekalowski, J. W., Prasad, A.: Studies on influenza virus I. Antigenic variation in influenza virus type C. Arch. ges. Virusforsch.42, 215–227 (1973).
de Watcher, R., Fiers, W.: Preparative two-dimensional polyacrylamide gel electrophoresis of32P-labeled RNA. Anal. Biochem.49, 184–197 (1972).
Dowdle, W. R., Davenport, F. M., Fukumi, H., Schild, G. C., Tumova, B., Webster, R. G., Zakstelskaja, L. Ya.: Orthomyxoviridae. Intervirology5, 245–251 (1975).
Fazekas de St. Groth, S., Webster, R. G.: Disquisitions on original antigenic sin. I. Evidence in man. J. exp. Med.124, 331–345 (1966).
Gerth, H.-J., Bauer, K. H., Steinitz, H.: Gibt es Hinweise auf eine Antigendrift bei Influenza C Viren? Zbl. Bakt. Hyg. I Abt. Org. A231 (1974).
Herrler, G., Compans, R. W., Meier-Ewert, H.: A precursor glycoprotein in influenza C virus. Virology99, 49–56 (1979).
Hirst, G. K.: The relationship of the receptors of a new strain of virus to those of the mumps-NDV-influenza group. J. exp. Med.91, 177–184 (1950).
Kendal, A. P.: A comparison of “influenza C” with prototype myxoviruses: Receptor-destroying activity (neuraminidase) and structural polypeptides. Virology65, 87–99 (1975).
Kilbourne, E. D.: The influenza viruses and influenza—an introduction. In:Kilbourne, E. D. (ed.), The influenza viruses and influenza, 1–13. New York: Academic Press 1975.
Meier-Ewert, H., Compans, R. W., Bishop, D. H. L., Herrler, G.: Molecular analyses of influenza C virus. In:Barry, R. D., Mahy, B. W. J. (eds.), Negative Strand Viruses and the Host Cell, 127–133. New York: Academic Press 1978.
Pereira, H. G.: Influenza: Antigenic spectrum Progr. med. Virol.11, 47–79 (1969).
Petri, T., Meier-Ewert, H., Compans, R. W.: Replication and plaque assay of influenza C virus in chicken kidney cells. FEMS Microbiol. Lett.5, 227–230 (1979).
Petri, T., Meier-Ewert, H., Compans, R. W.: Inhibition of influenza C virus replication by actinomycin D, α-amanitin, and uv irraditation. J. Virol.32, 1037 to 1040 (1979).
Racaniello, V. R., Palese, P.: Isolation of influenza C virus recombinants. J. Virol.32, 1006–1014 (1979).
Scholtissek, C., Rott, R.: Ribonucleic acid nucleotidyl transferase induced in chick fibroblasts after infection with an influenza virus. J. gen. Virol.4, 125–137 (1969).
Taylor, R. M.: Studies on survival of influenza virus between epidemics and antigenic variants of the virus. Amer. J. publ. Hlth.39, 171–178 (1949).
Taylor, R. M.: A further note on 1233 (“influenza C”;) virus. Arch. ges. Virusforsch.4, 485–500 (1951).
Webster, R. G., Laver, W. G.: Antigenic variation of influenza viruses. In:Kilbourne, E. D. (ed.), The Influenza Viruses and Influenza, 269–314. New York: Academic Press 1975.
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Meier-Ewert, H., Petri, T. & Bishop, D.H.L. Oligonucleotide fingerprint analyses of influenza C virion RNA recovered from five different isolates. Archives of Virology 67, 141–147 (1981). https://doi.org/10.1007/BF01318597
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DOI: https://doi.org/10.1007/BF01318597