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Nucleotide sequence of a 3.5 kilobase fragment of malignant catarrhal fever virus strain WC11

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Summary

A 3.5 kilobase DNA fragment of the malignant catarrhal fever virus (MCFV), strain WC11, was mapped with a number of restriction enzymes, subcloned and sequenced. The fragment was subcloned into plasmid vector, pUC19, for direct sequencing. A complete open reading frame of 2,058 base pairs and a partial open reading frame of 630 base pairs were identified. The sequence of 3,389 nucleotides was compared to other herpesviruses. A 310 base pairs sequence in gene A was 57% homologous to a sequence in reading frame BXLF1 of Epstein-Barr virus strain B95-8.

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References

  1. Devereux J (1989) The GCG sequence analysis software package, version 6.0. Genetics Computer Group, University of Wisconsin Biotechnology Center, Madison, Wisconsin

    Google Scholar 

  2. Baer R, Bankier AT, Biggin MD, Deininger PL, Farrell PJ, Gibson TJ, Hatfull G, Hudson GS, Satchwell SC, Seguin C, Tuffnell PS, Barrell BG (1984) DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature 310: 207–211

    Google Scholar 

  3. Edington N, Patel J, Russell PH, Plowright W (1979) The nature of the acute lymphoid proliferation in rabbits infected with the herpes virus of bovine malignant catarrhal fever. Eur J Cancer 15: 1515–1522

    Google Scholar 

  4. Herring AJ, Reid H, Inglis N, Pow I (1989) Immunoblotting analysis of the reaction of wildebeest, sheep and cattle sera with the structural antigens of alcelaphine herpesvirus-1 (malignant catarrhal fever virus). Vet Microbiol 19: 205–215

    Google Scholar 

  5. Hunt RD, Billup LH (1979) Wildebeest-associated malignant catarrhal fever in Africa: a neoplastic disease of cattle caused by an oncogenic herpesvirus? Comp Immunol Microbiol Infect Dis 2: 275–283

    Google Scholar 

  6. Kyte JM, Doolittle RF (1982) A simple method of displaying the hydropathic character of a protein. J Mol Biol 157: 105–132

    Google Scholar 

  7. Maniatis T, Fritsch EF, Sambrook J (1982) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, New York

    Google Scholar 

  8. McGeoch DJ, Dalrymple MA, Davison AJ, Dolan A, Frame MC, McNab D, Perry LJ, Scott JE, Taylor P (1988) The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1. J Gen Virol 69: 1531–1574

    Google Scholar 

  9. McKnight SL, Kingsbury R (1982) Transcriptional control signals of a eukaryotic protein-coding gene. Science 217: 316–324

    Google Scholar 

  10. Plowright W, Ferris RD, Scott GR (1960) Blue wildebeest and the aetiological agent of bovine malignant catarrhal fever. Nature 188: 1167–1169

    Google Scholar 

  11. Plowright W (1984) Malignant catarrhal fever virus: a lymphotropic herpesvirus of ruminants. In: Wittmann G, Gaskell RM, Rziha HJ (eds) Latent herpes virus infections in veterinary medicine. Martinus Nijhoff, for the Commission of the European Communities, Boston, pp 279–302

    Google Scholar 

  12. Plowright W (1986) Malignant catarrhal fever. Rev Sci Tech Off Int Epizool 5: 897–918

    Google Scholar 

  13. Reid HW, Pow I, Buxton D (1989) Antibody to alcelaphine herpesvirus-1 (AHV-1) in hamsters experimentally infected with AHV-1 and the ‘sheep-associated’ agent of malignent catarrhal fever. Res Vet Sci 47: 383–386

    Google Scholar 

  14. Roizman B, Carmichael LE, Deinhardt F, De The G, Nahmias AJ, Plowright W, Rapp F, Sheldrick P, Takahashi M, Wolf K (1981)Herpesviridae: definition, provisional nomenclature and taxonomy. Intervirology 16: 201–217

    Google Scholar 

  15. Roizman B, Batterson W (1985) Herpesviruses and their replication. In: Fields BN (ed) Virology. Raven Press, New York, pp 497–526

    Google Scholar 

  16. Rossiter PB (1981) Antibody to malignant catarrhal fever virus in sheep sera. J Comp Pathol 91: 303–311

    Google Scholar 

  17. Rossiter PB (1983) Antibodies to malignant catarrhal fever virus in cattle with non-widebeest-associated malignant catarrhal fever. J Comp Pathol 93: 93–97

    Google Scholar 

  18. Saiki RK, Gelfand DH, Stoffel S, Scharf ST, Hinguchi R, Horn GT, Mullis KB, Erlich HA (1988) Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239: 487–491

    Google Scholar 

  19. Sanger F, Miklen S, Coulson AR (1977) DNA sequencing with Chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463–5467

    Google Scholar 

  20. Schulte-Holthausen H, zur Hausen H (1970) Purification of the Epstein-Barr virus and some properties of its DNA. Virology 40: 776–779

    Google Scholar 

  21. Seal BS, Klieforth RB, Welch WH, Heuschele WP (1989) Alcelaphine herpes virus 1 and 2 SDS-PAGE analysis of virion polypeptides, restriction endonuclease analysis of genomic DNA and virus replication restriction in different cell types. Arch Virol 106: 301–320

    Google Scholar 

  22. Shih LM, Irving JM, Zee YC, Pritchett RP (1988) Cloning and characterization of a genomic probe for malignant catarrhal fever virus. Am J Vet Res 49: 1665–1668

    Google Scholar 

  23. Shih LM, Zee YC, Castro AE (1989) Comparison of genomes of malignant catarrhal fever-associated herpesvirus isolates by restriction endonuclease analysis. Arch Virol 109: 145–151

    Google Scholar 

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Hsu, D., Shih, L.M. & Zee, Y.C. Nucleotide sequence of a 3.5 kilobase fragment of malignant catarrhal fever virus strain WC11. Archives of Virology 113, 53–60 (1990). https://doi.org/10.1007/BF01318352

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  • DOI: https://doi.org/10.1007/BF01318352

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