Skip to main content
SpringerLink
Log in

Comparative genome mapping of bovine encephalitis herpesvirus, bovine herpesvirus 1, and buffalo herpesvirus

  • Original Papers
  • Published:
Archives of Virology Aims and scope Submit manuscript

Summary

A clone library of 11 of 15BamHI fragments representing 81% of the 140 kilobase DNA genome of the prototype bovine encephalitis herpesvirus strain N569 (BEHV.N569) was constructed. The clones were used to verify theBamHI,BstEII,EcoRI, andHindIII genomic maps for BEHV.N569 published by Engels et al. [Virus Res 6: 57–73 (1986)] for the same virus although some amendments/variations to theBamHI map were found in that 3 previously unidentified restriction sites were identified. Restriction site maps forBglII andKpnI were also derived for BEHV.N569.

Southern blot analysis using32P-labelled BEHV DNA as probe indicated that bovine herpesvirus 1 (BHV1), buffalo herpesvirus 1 (BuHV1) and caprine herpesvirus 1 (CaHV1) were similar and that the similarity occurred throughout the entire length of the genomes; CaHV1 was more distantly related to the other 3 viruses. Because of the similarities BEHV.N569 and BHV1.Cooper cloned DNA fragments were used to constructBamHI,BglII,BstEII,EcoRI,KpnI, andHindIII restriction site maps for the genome of BuHV1 andBamHI,BglII, andKpnI maps for the genome of BHV1.V155, a genital strain.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Andino RH, Torres HN, Polacino PS, Schudel A, Palma L (1987) Detection of bovine herpesvirus 1 nucleic acid sequences using a dot-blot hybridization procedure. Am J Vet Res 48: 948–987

    Google Scholar 

  2. Bagust TJ (1972) Comparison of the biological, biophysical and antigenic properties of four strains infectious bovine rhinotracheitis herpesvirus. J Com Path 82: 365–375

    Google Scholar 

  3. Bagut TJ, Clarke L (1972) Pathogenesis of meningoencephalitis produced in calves by infectous bovine rhinotracheitis herpesvirus. J Comp Pathol 82: 375–383

    Google Scholar 

  4. Bartha A, Hajdu G, Aldasy P, Paczolay G (1969) Occurrence of encephalitis caused by infectious bovine rhinotracheitis virus in calves in Hungary. Acta Vet Hung 19: 145–151

    Google Scholar 

  5. Brake F, Studdert MJ (1985) Molecular epidemiology and pathogenesis of ruminant herpesviruses including bovine, buffalo and caprine herpesvirus 1 and bovine encephalitis herpesvirus. Aust Vet J 62: 331–334

    Google Scholar 

  6. Carillo BJ, Ambrogi A, Schudel A, Vazquez M, Dahme E, Pospischil A (1983) Meningoencephalitis caused by IBR virus in calves in Argentina. J Vet Med B 30: 327–332

    Google Scholar 

  7. Carillo BJ, Pospischil A, Dahme E (1983) Pathology of a bovine viral necrotizing encephalitis in Argentina. Zentralbl Veterinarmed [B]30: 161–168

    Google Scholar 

  8. Engels M, Giuliani C, Wild P, Beck TM, Loepfe E, Wyler R (1986) The genome of bovine herpesvirus 1 (BHV-1) strains exhibiting a neuropathogenic potential compared to known BHV-1 strains by restriction site mapping and cross-hybridization. Virus Res 6: 57–73

    Google Scholar 

  9. Engels M, Loepfe E, Wild P, Schraner E, Wyler R (1987) The genome of caprine herpesvirus 1: genome structure and relatedness to bovine herpesvirus 1. J Gen Virol 68: 2019–2023

    Google Scholar 

  10. Eugster AK, Angulos AB, Jones LP (1974) Herpesvirus encephalitis in range calves. In: Proc 17th Ann Meet Amer Assoc Vet Lab Diag, pp 267–290

  11. French EL (1962a) A specific virus encephalitis in calves: isolation and characterization of the causal agent. Aust Vet J 38: 216–221

    Google Scholar 

  12. French EL (1962b) Relationship between infectious bovine rhinotracheitis (IBR) virus and a virus isolated from calves with encephalitis. Aust Vet J 38: 555–556

    Google Scholar 

  13. Friedli K, Metzler AE (1987) Reactivity of monoclonal antibodies to protein of a neurotropic bovine herpesvirus 1 (BHV-1) strain. Arch Virol 94: 109–122

    Google Scholar 

  14. Gardiner MR, Nairn ME, Siera M (1964) Viral meningoencephalitis of calves in Western Australia. Aust Vet J 40: 225–228

    Google Scholar 

  15. Gielkens ALJ, van Oirschot JT, Berns AJM (1985) Genome differences among field isolates and vaccine strains of pseudorabies virus. J Gen Virol 66: 69–82

    Google Scholar 

  16. Hall WTK, Simmons GC, French EL, Snowdon WA, Asdell M (1966) The pathogenesis of encephalitis virus caused by infectious bovine rhinotracheitis virus. Aust Vet J 42: 229–237

    Google Scholar 

  17. Hill BD, Hill MWM, Chung YS, Whittle RJ (1984) Meningoencephalitis in calves due to bovine herpesvirus type 1 infection. Aust Vet J 61: 242–243

    Google Scholar 

  18. Magyar G, Benko M, Harrach L, Kucsera L, Bartha A (1989) DNA restriction enzyme analysis of a bovine herpesvirus 1 stain isolated from encephalitis in Hungary. Acta Vet Hung 37: 3–4

    Google Scholar 

  19. Maniatis T, Fritsch EF, Sambrook J (1982) Molecular cloning, a laboratory manual. Cold Spring Harbour, New York

    Google Scholar 

  20. Mayfield JE, Good PJ, van Oort HJ, Campbell AR, Reed DE (1983) Cloning and cleavage site mapping of DNA from bovine herpesvirus 1 (Cooper strain). J Virol 47: 259–264

    Google Scholar 

  21. Metzler AE, Schudel A, Engels M (1986) Bovine herpesvirus 1: molecular and antigenic characteristics of variant viruses isolated from calves with neurological disease. Arch Virol 87: 205–217

    Google Scholar 

  22. Pignatti PF, Cassai E, Meneguzzi G, Chenciner B, Milanesi G (1979) Herpes simplex virus DNA isolation from infected cells with a novel procedure. Virology 93: 260–264

    Google Scholar 

  23. Roizman B (1982) In: Roizman B (ed) The family Herpesviridae: general description taxonomy and classification, vol 1, chap 1, the herpesviruses, Plenum Press, New York

    Google Scholar 

  24. Schudel AA, Carillo BJ, Wyler R, Metzler AE (1986) Infections of calves with antigenic variants of bovine herpesvirus-1 (BHV-1) and neurological disease. J Vet Med B 33: 303–310

    Google Scholar 

  25. Seal BS, St Jear SC, Taylor RE (1985) Restriction endonuclease analysis of bovine herpesvirus-1 DNA and nucleic acid homology between isolates. J Gen Virol 66: 2787–2792

    Google Scholar 

  26. Snowdon WA (1964) Infectious bovine rhinotracheitis and infectious pustular vulvo-vaginitis in Australian cattle. Aust Vet J 40: 277–288

    Google Scholar 

  27. St George TD, Philpott M (1972) Isolation of IBR virus from the prepuce of water buffalo bulls in Australia. Aust Vet J 48: 126

    Google Scholar 

  28. Studdert MJ (1989) Bovine encephalitis herpesvirus. Vet Rec 125: 584

    Google Scholar 

  29. Studdert MJ, Wilks CR, Coggins L (1974) Antigenic comparisons and serological survey of equine adenoviruses. Am J Vet Res 36: 693–699

    Google Scholar 

  30. Studdert MJ, Brake F, Browning GF (1981) Bovine encephalitis herpesvirus is different from bovine herpesvirus 1 and from other ruminant herpesviruses. In: Proc international conference on veterinary preventative medicine and animal production, Melbourne, 1985, pp 149–150

  31. Tisdall DJ, Bentley CB, Collins DM, Horner GW (1984) New Zealand caprine herpesvirus: Comparison with an Australian isolate and with bovine herpesvirus type 1 by restriction endonuclease analysis. NZ Vet J 32: 99–100

    Google Scholar 

  32. Weiblen R, Lombardo de Barios CS, Canabarro TF, Flores IE (1989) Bovine meningoencephalitis from IBR virus. Vet Rec 124: 666–667

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. School of Veterinary Science, The University of Melbourne, Parkville, Victoria, Australia

    D. M. Bulach & M. J. Studdert

Authors
  1. D. M. Bulach
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. J. Studdert
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bulach, D.M., Studdert, M.J. Comparative genome mapping of bovine encephalitis herpesvirus, bovine herpesvirus 1, and buffalo herpesvirus. Archives of Virology 113, 17–34 (1990). https://doi.org/10.1007/BF01318350

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01318350

Keywords

Search

Navigation