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Infection of newborn and fetal hamsters induced by inoculation of Lu III parvovirus

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Summary

The Lu III parvovirus was adapted to the newborn hamster and produced a systemic infection with massive intestinal hemorrhage. Inoculation of pregnant hamsters lead to transplacental infection of the fetuses and abortion. Most fetal deaths were observed in animals inoculated on days 8 and 10 of gestation. Virus was recovered from dead fetuses, placentas, and viable fetuses. Histological lesions were found in the heart, liver, kidney and CNS of infected fetuses.

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Authors and Affiliations

  1. International Center of Environmental Safety, Albany Medical College, Holloman Air Force Base, New Mexico, USA

    K. F. Soike, M. Iatropoulis & G. Siegl

  2. Institut für Medizinische Mikrobiologie, Universität Bern, CH-3008, Bern, Switzerland

    G. Siegl

  3. Delta Regional Primate Research Center, Tulane University, 70433, Covington, LA, USA

    K. F. Soike

Authors
  1. K. F. Soike
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  2. M. Iatropoulis
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  3. G. Siegl
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Soike, K.F., Iatropoulis, M. & Siegl, G. Infection of newborn and fetal hamsters induced by inoculation of Lu III parvovirus. Archives of Virology 51, 235–241 (1976). https://doi.org/10.1007/BF01318027

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  • DOI: https://doi.org/10.1007/BF01318027

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