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Antiviral activity of virus-like particles fromLentinus edodes (Shiitake)

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Interferon (IF) induction and antiviral activity by purified spherical (S) or filamentous (F) virus-like particles and S-derived RNA was studied. A single administration of S particles prior to virus challenge reduced significantly the mortality of mice infected with western equine encephalitis (WEE) virus.

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Takehara, M., Kuida, K. & Mori, K. Antiviral activity of virus-like particles fromLentinus edodes (Shiitake). Archives of Virology 59, 269–274 (1979).

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