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Action of 6-(p-hydroxyphenylazo)-uracil on bacteriophage IG 1

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Summary

IG 1, a temperate phage ofBacillus subtilis, is strongly induced from its lysogens by 6-(p-hydroxyphenylazo)-uracil, an azopyrimidine known as selectively inhibiting theB. subtilis DNA polymerase III. IG 1 phages originated either by induction or infection multiply, abundantly, in the presence of that azopyrimidine, in spite of the drastic decline of cell viability. Chloramphenicol completely suppresses the induction effect and also blocks the formation of spontaneously induced phage particles.

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Fernandes, R.M., de Lencastre, H. & Archer, L.J. Action of 6-(p-hydroxyphenylazo)-uracil on bacteriophage IG 1. Archives of Virology 113, 177–181 (1990). https://doi.org/10.1007/BF01316671

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  • DOI: https://doi.org/10.1007/BF01316671

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