Digestive Diseases and Sciences

, Volume 38, Issue 3, pp 542–545 | Cite as

Colonic mucosal pH in humans

  • Carl J. McDougall
  • Ronald Wong
  • Peter Scudera
  • Martin Lesser
  • Jerome J. DeCosse
Original Articles


Mucosal pH was measured at specific anatomic segments within the colon using a flexible pH probe in patients prepared for colonoscopy. The data revealed similar pH measurements along the length of the colon, irrespective of the presence or absence of colorectal neoplasia. Patients exhibited a relatively acidic right colon; a more alkaline transverse, left, and sigmoid colon; and a relatively acidic rectum. There were no apparent genderor age-related effects on colonic mucosal pH.

Key Words

mucosa pH colon 


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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • Carl J. McDougall
    • 1
    • 2
  • Ronald Wong
    • 1
    • 2
  • Peter Scudera
    • 1
    • 2
  • Martin Lesser
    • 1
    • 2
  • Jerome J. DeCosse
    • 1
    • 2
  1. 1.Departments of Medicine and SurgeryCornell University Medical CollegeNew York
  2. 2.Division of Biostatistics at North Shore University Hospital-Cornell University Medical CollegeNew York

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