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Inhibition of glycosylation processing alters the growth parameters of cells transformed by the oncogene of Simian Sarcoma virus

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Summary

Normal rat kidney (NRK) cells transformed by the v-sis oncogene of Simian Sarcoma virus (SSV) were treated with the glucosidase I inhibitor castanospermine. The inhibitor did not change cell morphology, but specific growth parameters such as serum- and anchorage-independence were lost.

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Authors and Affiliations

  1. Institut für Medizinische Virologie, Justus-Liebig-Universität Giessen, Giessen, Germany

    A. Hadwiger-Fangmeier, H. Niemann & T. Tamura

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  1. A. Hadwiger-Fangmeier
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  2. H. Niemann
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  3. T. Tamura
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Hadwiger-Fangmeier, A., Niemann, H. & Tamura, T. Inhibition of glycosylation processing alters the growth parameters of cells transformed by the oncogene of Simian Sarcoma virus. Archives of Virology 104, 339–345 (1989). https://doi.org/10.1007/BF01315555

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  • DOI: https://doi.org/10.1007/BF01315555

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