Skip to main content
SpringerLink
Log in

Polyethylene glycol-mediated infection with avian sarcoma viruses

  • Brief Report
  • Published:
Archives of Virology Aims and scope Submit manuscript

Summary

In this communication we report that fusion of viral and cellular membranes by polyethylene glycol is a convenient approach to overcoming genetically determined resistance to infection. Using this method, avian sarcoma virus-transformed mammalian cells have been produced which serve as useful model systems for the study of Rous sarcoma virus-specific tumor antigens.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bauer, H.: Virion and tumor cell antigens of C-type RNA tumor viruses. Adv. Cancer Res.20, 275–340 (1974).

    Google Scholar 

  2. Becker, D., Kurth, R., Critchley, D., Friis, R. R., Bauer, H.: Distinguishable transformation-defective phenotypes among temperature-sensitive mutants of Rous sarcoma virus. J. Virol.21, 1042–1055 (1977).

    Google Scholar 

  3. de Giuli, C., Kawai, S., Dales, S., Hanafusa, H.: Absence of surface projections on some noninfectious forms of RSV. Virology66, 253–260 (1975).

    Google Scholar 

  4. Friis, R. R.: Abortive infection of Japanese quail cells with avian sarcoma viruses. Virology50, 701–712 (1972).

    Google Scholar 

  5. Halpern, M. S., Bolognesi, D. P., Friis, R. R.: Viral glycoprotein synthesis studies in an established line of Japanese quail embryo cells infected with the Bryan high-titer strain of Rous sarcoma virus. J. Virol.18, 504–510 (1976).

    Google Scholar 

  6. Hanafusa, T., Miyamoto, T., Hanafusa, H.: A type of chick embryo cell that fails to support formation of infectious RSV. Virology40, 55–64 (1970).

    Google Scholar 

  7. Ogura, H., Friis, R. R.: Further evidence for the existence of a viral envelope protein defect in the Bryan high-titer strain of Rous sarcoma virus. J. Virol.16, 443–446 (1975).

    Google Scholar 

  8. Pontecorvo, G.: Production of mammalian cell hybrids by means of polyethylene glycol treatment. Somat. Cell Genet.1, 397–400 (1975).

    Google Scholar 

  9. Scheele, C. M., Hanafusa, H.: Proteins of helperdependent RSV. Virology45, 401–410 (1971).

    Google Scholar 

  10. Steck, F. T., Rubin, H.: The mechanism of interference between avian leukosis virus and Rous sarcoma virus. II. Early steps of infection by RSV of cells under conditions of interference. Virology29, 642–653 (1966).

    Google Scholar 

  11. Vogt, P. K.: Envelope classification of avian RNA tumor viruses. Bibl. Haemat.36, 153–167 (1970).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Virologie, Fachbereich Humanmedizin, Justus Liebig-Universität Giessen, Germany

    W. Rohde, G. Pauli, Juliane Henning & R. R. Friis

Authors
  1. W. Rohde
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Pauli
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Juliane Henning
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. R. Friis
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rohde, W., Pauli, G., Henning, J. et al. Polyethylene glycol-mediated infection with avian sarcoma viruses. Archives of Virology 58, 55–59 (1978). https://doi.org/10.1007/BF01315535

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01315535

Keywords

Search

Navigation