Summary
The restriction enzymes Eco RI, Hind III and Pst I have been used to show that 5 adenovirus type 2 isolates can be divided into 2 genome types and within each type there are different genome variations.
References
Aird, F., King, J. J., Younghusband, H. B.: Identification of a new strain of adenovirus type 2 by restriction endonuclease analysis. Gene22, 133–134 (1983).
de Jong, J. C., Wigand, R., Kidd, A. H., Wadell, G., Kapsenberg, J. G., Muzerie, C. J., Wermenbol, A. G., Firtzlaff, R. G.: Candidate adenoviruses 40 and 41: fastidious adenoviruses from human infant stool. J. Med. Virol.11, 215–231 (1983).
Eizuru, Y., Inagawa, S., Minamishima, Y.: Application of “Hirt Supernatant” DNA to the Molecular Epidemiology of Cytomegalovirus Infections. J. Clin. Microbiol.20, 1012–1014 (1984).
Fife, K. H., Ashley, R., Corey, L.: Isolation and characterization of six new genome types of human adenovirus types 1 and 2. J. Clin. Microbiol.21, 20–23 (1985).
Grillner, L., Blomberg, I.: Restriction enzyme analysis of human cytomegalovirus using DNA extracted from infected cells. J. Med. Virol.14, 313–322 (1984).
Isreal, M. S.: The viral flora of enlarged tonsils and adenoids. J. Pathol. Bacteriol.84, 169–176 (1962).
Kemp, M. C., Hierholzer, J. C., Cabradilla, C. P., Obijeski, J. F.: The changing etiology of epidemic keratoconjunctivitis: antigenic and restriction enzyme analyses of adenovirus types 19 and 37 isolated over a 10-year period. J. Infect. Dis.148, 24–33 (1983).
Kidd, A. H.: Genome variants of adenovirus 41 (subgroup G) from children with diarrhoea in South Africa. J. Med. Virol.14, 49–59 (1984).
Kidd, A. H., Berkowitz, F. E., Blaskovic, P. J., Schoub, B. D.: Genome variants of human adenovirus 40 (subgroup F). J. Med. Virol.14, 235–246 (1984).
Lambriex, M., van der Veen, J.: Comparison of replication of adenovirus type 2 and type 4 in human lymphocyte cultures. Infect. Immun.14, 618–622 (1976).
McFarlane, E. S., James, H.: Characterization ofHerpes simplex viral DNA using3H-thymidine and restriction endonuclease analysis. Med. Lab. Sci.41, 73–75 (1984).
van der Veen, J., Lambriex, M.: Relationship of adenovirus to lymphocytes in naturally infected human tonsils and adenoids. Infect. Immun.7, 604–609 (1973).
Wadell, G., Varsanyi, T. M.: Demonstration of three different subtypes of adenovirus type 7 by DNA restriction site mapping. Infect. Immun.21, 238–246 (1978).
Wadell, G., Hammarskjold, M. L., Winberg, G., Varsanyi, T. M., Sundell, G.: Genetic variability of adenoviruses. Ann. N.Y. Acad. Sci.354, 16–42 (1980).
Wadell, G., de Jong, J. C.: Restriction endonucleases in identification of a genome type of adenovirus 19 associated with Keratoconjunctivitis. Infect. Immun.27, 292–296 (1980).
Wadell, G., Varsanyi, T. M., Lord, A., Sutton, R. N. P.: Epidemic outbreaks of adenovirus 7 with special reference to the pathogenicity of adenovirus genome type 7b. Am. J. Epidemiol.112, 619–628 (1980).
Wadell, G., de Jong, J. C., Wolontis, S.: Molecular epidemiology of adenoviruses: alternating appearance of two different genome types of adenovirus 7 during epidemic outbreaks in Europe from 1958 to 1980. Infect. Immun.34, 368–372 (1981).
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McFarlane, E.S., Stewart, J.H.B. & James, H. Genome variation of 5 clinical adenovirus type 2 isolates determined by restriction enzyme digestion analysis. Archives of Virology 87, 321–326 (1986). https://doi.org/10.1007/BF01315310
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DOI: https://doi.org/10.1007/BF01315310