Summary
Resistance to ureain vitro at 37° C varied for each FMDV strain analysed. The urea marker did not correlate with other markers such as resistance to acid, resistance to acidity or size of plaques under agar on BHK21/13 cells.
The resistance to urea of subtypes A24 Cruzeiro, O1 Caseros and C3 Resende varied in accordance with their antigenic potency when administered to swine as a trivalent water-in-oil emulsion type vaccine.
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Maes, R.F., Gomes, I. & Augé de Mello, P. Susceptibility of various FMDV strains to urea. Archives of Virology 56, 353–358 (1978). https://doi.org/10.1007/BF01315287
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DOI: https://doi.org/10.1007/BF01315287