Summary
Rate zonal and buoyant density gradient centrifugation did not reveal any difference between tick-borne encephalitis virus virions released from acutely or persistently infected cells. All three RNA species characteristic for flavivirus replication were found both in acutely or persistently infected cells, but increased levels of intracellular 42S RNA polyadenylation was observed in persistently infected cells.
Similar content being viewed by others
References
Andzhaparidze, O. G., Bogomolova, N. N., Boriskin, Yu. S.: Properties of tick-borne encephalitis virus persisting in chronically infected cell culture for a long time. Probl. Virol. (Russian)2, 192–195 (1978).
Andzhaparidze, O. G., Rozina, E. E., Bogomolova, N. N., Boriskin, Yu. S.: Morphological characteristics of the infection of animals with tick-borne encephalitis virus persisting for a long time in cell cultures. Acta virol.22, 218–224 (1978).
Bogomolova, N. N., Schuchmina, N. R., Andzhaparidze, O. G.: Investigation of the intensity of tick-borne encephalitis virus reproduction in different cell systems. Probl. Virol. (Russian)3, 301–305 (1971).
Boulton, R. W., Westaway, E. G.: Togavirus RNA: reversible effect of urea on genomes and absence of subgenomic viral RNA in Kunjin virus-infected cells. Arch. Virol.55, 201–208 (1977).
Darnell, M. B., Koprowski, H.: Genetically determined resistance to infection with group B arboviruses. II. Increased production of interfering particles in cell cultures from resistant mice. J. inf. Dis.129, 248–256 (1974).
Frey, T. K., Strauss, J. H.: Replication of Sindbis virus. VI. Poly (A) and poly (U) in virus-specific RNA species. Virology86, 494–506 (1978).
Hruby, D. E.: Effect of polyadenilic acid on the functional half-life of encephalomyocarditis virus RNA during translation. Biochem. biophys. Res. Comm.81, 1425–1434 (1978).
Martin, S. J., ter Meulen, V.: A rapid method for the quantitative study of RNA from canine distemper virus infected cells. J. gen. Virol.32, 321–325 (1976).
Nishimura, C., Tsukeda, H.: Replication and synthesis of Japanese encephalitis virus ribonucleic acids in Vero cells. Japan. J. Microbiol.15, 309–316 (1971).
Perry, R. P., la Torre, J., Kelley, D. E., Greenberg, J. R.: On the lability of poly (A) sequences during extraction of messenger RNA from polyribosomes. Biochim. biophys. Acta262, 220–226 (1972).
Schmaljohn, C., Blair, C. D.: Persistent infection of cultured mammalian cells by Japanese encephalitis virus. J. Virol.24, 580–589 (1977).
Soloviev, G. Ya., Bogomolova, N. N., Andzhaparidze, O. G.: A study of the tick-borne encephalitis virus RNA synthesis in cell culture. Probl. Virol. (Russian)3, 305–308 (1971).
Trent, D. W., Swensen, C. C., Qureshi, A. A.: Synthesis of Saint Louis encephalitis virus ribonucleic acid in BHK-21/13S cells. J. gen. Virol.3, 385–394 (1969).
Villarreal, L. P., Holland, J. J.: RNA synthesis in BHK-21 cells persistently infected with vesicular stomatitis virus and rabies virus. J. gen. Virol.33, 213–224 (1976).
Wengler, G., Wengler, G., Gross, H. J.: Studies on virus-specific nucleic acids synthesized in vertebrate and mosquito cells infected with flaviviruses. Virology89, 423–437 (1978).
Zebovitz, E., Leong, J. L., Doughty, S. C.: Japanese encephalitis virus replication: a procedure for selective isolation and characterization of viral RNA species. Arch. ges. Virusforsch.38, 319–327 (1972).
Zhdanov, V. M., Gavrilov, V. I., Bogomolova, N. N., Klimenko, S. M., Andzhaparidze, O. G.: Biochemical study of HEp-2 cells chronically infected with tick-borne encephalitis virus. Rev. Roum. Virol.25, 75–89 (1974).
Zhdanov, V. M., Bogomolova, N. N., Gavrilov, V. I., Andzhaparidze, O. G., Deryabin, P. G., Astakhova, A. N.: Infectious DNA of tick-borne encephalitis virus. Arch. ges. Virusforsch.45, 215–224 (1974).
Author information
Authors and Affiliations
Additional information
With 2 Figures
Rights and permissions
About this article
Cite this article
Andzhaparidze, O.G., Boriskin, Y.S., Drynov, I.D. et al. A comparative study of tick-borne encephalitis virus RNA synthesis in acutely and persistently infected cells. Archives of Virology 61, 305–312 (1979). https://doi.org/10.1007/BF01315017
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01315017