Summary
In vaccinia virus infected cells the appearance of a late enzyme RNA polymerase was prevented by MPB, an inhibitor of nucleolar RNA synthesis, although inductions of the early enzymes thymidine kinase and DNA polymerase were not affected. It is inferred that nucleoli may be involved in the replication of vaccinia virus.
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Nishigori, H., Nishimura, C. Failure of poxvirus replication in the presence of an inhibitor of nucleolar RNA synthesis. Archives of Virology 53, 163–166 (1977). https://doi.org/10.1007/BF01314857
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DOI: https://doi.org/10.1007/BF01314857