Summary
High doses of rabbit interferon (2×106 and 2×105 units/ml, a drop of about 0.1 ml administered topically into the eye twice daily) suppressed the rejection of rabbit corneal xenograft, whereas a low dose (2×103 units/ml) enhanced it. However, neither heat-inactivated rabbit interferon nor mouse L cell interferon showed any effects on rabbit corneal grafts.
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Imanishi, J., Oishi, K., Kishida, T. et al. Effects of interferon preparations on rabbit corneal xenograft. Archives of Virology 53, 157–161 (1977). https://doi.org/10.1007/BF01314856
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DOI: https://doi.org/10.1007/BF01314856