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Antitumor effect of virus-like particles fromLentinus edodes (Shiitake) on Ehrlich ascites carcinoma in mice


Antitumor activities of two types of purified virus-like particles (S and F) fromLentinus edodes (Shiitake) and of S-derived RNA were studied in mice. Multiple administration of the particles or of the RNA markedly reduced the mortality of mice injected with Ehrlich ascites carcinoma cells.

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Takehara, M., Mori, K., Kuida, K. et al. Antitumor effect of virus-like particles fromLentinus edodes (Shiitake) on Ehrlich ascites carcinoma in mice. Archives of Virology 68, 297–301 (1981).

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